[Recurrence problems with preventive primaquine treatment in patients with malaria].

Author: BygbjergI C, RønnA M

Paper Details 
Original Abstract of the Article :
Standard treatment of P. ovale and P. vivax malaria is 1500 mg of chloroquine base given over three days followed by 15 mg of primaquine base daily for 14 days. At the Department of Infectious Diseases, Rigshospitalet, Copenhagen an increasing number of cases of relative by primaquine-resistant mala...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8273193

データ提供:米国国立医学図書館(NLM)

Primaquine: A Delicate Balance in the Desert of Malaria Treatment

Malaria, like a persistent desert wind, has plagued humanity for centuries. This study, like a seasoned traveler navigating the treacherous landscape of malaria treatment, explores the challenges associated with preventive primaquine treatment. The researchers, like explorers seeking a cure, investigate the increasing prevalence of relative primaquine-resistant malaria and the potential for serious side effects, including methaemoglobin formation and haemolytic anaemia, particularly in individuals with erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) deficiency. This study, like a map through the desert, offers valuable insights into the complexities of malaria treatment and the importance of careful patient monitoring.

Primaquine Resistance: An Evolving Challenge

This study, like a desert oasis threatened by drought, reveals the growing challenge of primaquine resistance in malaria treatment. The findings suggest that a significant number of patients are experiencing relapses after taking standard doses of primaquine. This resistance, like a shifting sand dune, requires a reassessment of treatment strategies and a need for increased vigilance in monitoring patient responses.

Navigating the Sands of Malaria Treatment: A Balancing Act

Malaria is a serious and potentially deadly disease requiring careful and individualized treatment. This study highlights the importance of balancing the benefits of primaquine with the risks of side effects. The findings emphasize the need for increased awareness of primaquine resistance and its potential consequences. It is crucial to consult with a healthcare professional for proper diagnosis and treatment, especially when dealing with malaria and its complexities.

Dr.Camel's Conclusion

This study, like a warning beacon in the desert, reminds us of the constant need for vigilance and adaptability in the fight against malaria. By understanding the challenges of primaquine resistance and its potential side effects, we can strive to provide more effective and safer treatment options for those affected by this devastating disease.

Date :
  1. Date Completed 1994-02-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8273193

DOI: Digital Object Identifier

8273193

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