The in vitro effects of ceftibuten on the host defense mechanism.

Author: BlasiF, BragaP C, Dal SassoM, MaciS, PiattiG

Paper Details 
Original Abstract of the Article :
The in vitro effects of ceftibuten on human polymorphonuclear leukocyte (PMN) chemotaxis, phagocytosis and chemiluminescence were investigated. PMN from healthy adult donors were incubated for 1 h in medium alone or in medium containing increasing concentrations of ceftibuten (4, 8 and 40 times the ...See full text at original site
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引用元:
https://doi.org/10.1159/000239168

データ提供:米国国立医学図書館(NLM)

Ceftibuten and the Immune System: A Tale of Two Worlds

This research delves into the intricate world of the immune system, investigating the potential impact of ceftibuten, a common antibiotic, on the function of human polymorphonuclear leukocytes (PMNs), essential components of the innate immune response. The study meticulously examined the effects of ceftibuten on PMN chemotaxis, phagocytosis, and chemiluminescence, aiming to assess the antibiotic's potential influence on these critical immune functions. The researchers carefully explored a range of ceftibuten concentrations, seeking to determine whether this antibiotic might interfere with the ability of PMNs to effectively combat infections. The study's findings offer insights into the potential interactions between ceftibuten and the immune system, providing a valuable perspective for understanding the antibiotic's overall impact on the body.

Ceftibuten: Balancing Antibacterial Power with Immune Function

This research delves into the potential impact of ceftibuten, a common antibiotic, on the immune system. The researchers found that ceftibuten, even at high concentrations, did not significantly interfere with the function of PMNs, suggesting that this antibiotic may have a relatively benign impact on the immune system. This finding is significant, as it suggests that ceftibuten can effectively combat infections without compromising the body's natural defenses. The study provides valuable insights into the safety and effectiveness of ceftibuten, offering a more nuanced understanding of its potential interactions with the immune system.

Navigating the Shifting Sands of Antibiotic Therapy

This research sheds light on the complex landscape of antibiotic therapy, underscoring the importance of understanding the potential interactions between antibiotics and the immune system. The study's findings suggest that ceftibuten may be a relatively safe and effective antibiotic, capable of combating infections without significantly compromising the body's natural defenses. This research provides valuable insights for healthcare professionals, guiding their decision-making process regarding the use of ceftibuten.

Dr.Camel's Conclusion

Dr. Camel believes that this research offers a valuable perspective on the delicate dance between antibiotic therapy and immune function. The study's findings suggest that ceftibuten may be a reliable and safe antibiotic, capable of effectively combating infections without significantly compromising the body's natural defenses. By understanding the potential interactions between antibiotics and the immune system, we can make more informed decisions about antibiotic therapy, ensuring that patients receive the most effective and safe treatment possible.
Date :
  1. Date Completed 1994-03-17
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

8306814

DOI: Digital Object Identifier

10.1159/000239168

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Languages

English

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