Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication.

Author: BlajchmanA, EliopoulosC, ItoS, KorenG, StephensonM

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Our objective was to characterize the short-term effects of maternal medications on breast-fed infants. STUDY DESIGN: A cohort of 838 infants breast-fed by women who were taking medications was prospectively studied, and the incidence of adverse reactions in the infants during maternal t...See full text at original site
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引用元:
https://doi.org/10.1016/s0002-9378(11)90771-6

データ提供:米国国立医学図書館(NLM)

Maternal Medications and Breastfeeding: A Prospective Study

Breastfeeding is a cornerstone of infant health and development, but concerns often arise regarding the safety of maternal medications during this period. This study investigates the short-term effects of maternal medications on breastfed infants. Researchers prospectively studied a cohort of 838 infants breastfed by women who were taking medications, meticulously documenting the incidence of adverse reactions in the infants during maternal therapy through telephone interviews.

Minor Adverse Reactions in a Small Percentage of Infants

The study revealed reassuring findings. No major adverse reactions necessitating medical attention were observed in the 838 breastfed infants. However, 94 women (11.2%) reported minor adverse reactions in their infants that did not require medical attention. The most common minor adverse effects varied among drug categories, with antibiotics causing diarrhea, analgesics or narcotics causing drowsiness, antihistamines causing irritability, and sedatives, antidepressants, or antiepileptics causing drowsiness.

A Desert Oasis for Breastfeeding Mothers

This study is like a refreshing oasis in the vast desert of maternal medication concerns. It provides valuable information, reassuring mothers that the short-term effects of most maternal medications on their breastfed infants are generally mild and pose little risk.

Dr. Camel's Conclusion

This study provides valuable data on the safety of breastfeeding during maternal therapy, emphasizing the importance of continued research to further evaluate the long-term effects of medications on breastfed infants. The study also highlights the importance of open communication between mothers, their healthcare providers, and lactation consultants to ensure informed decision-making regarding breastfeeding and medication use.

Date :
  1. Date Completed 1993-06-22
  2. Date Revised 2019-06-15
Further Info :

Pubmed ID

8498418

DOI: Digital Object Identifier

10.1016/s0002-9378(11)90771-6

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SNS
PICO Info
in preparation
Languages

English

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