[Effects of mebendazole on glucose, glycogen, lactic acid, and lactate dehydrogenase in Echinococcus granulosus cyst wall].

Author: ChaiJ J, FengJ J, GuoH F, JiaoP Y, XiaoS H, YaoM Y

Paper Details 
Original Abstract of the Article :
The glucose, glycogen, and lactic acid contents in Echinococcus granulosus cyst wall were 3570 +/- 623, 1276 +/- 126, and 267 +/- 29 micrograms.g-1, respectively. The lactate dehydrogenase (LDH) activity in the cyst wall was 4307 +/- 297 U/(min.mg protein). When infected mice were treated ig with me...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8503286

データ提供:米国国立医学図書館(NLM)

Effects of Mebendazole on Echinococcus granulosus Cyst Wall

Echinococcus granulosus, a type of parasitic worm, is like a persistent desert sandstorm, causing harm and disrupting the normal function of its host. This study investigates the effects of mebendazole, an anti-parasitic drug, on the cyst wall of Echinococcus granulosus. The researchers found that mebendazole significantly reduced the glucose and glycogen contents in the cyst wall, suggesting its potential to weaken the parasite's energy supply.

Mebendazole's Impact on Parasite Energy Supply

This study suggests that mebendazole can effectively target the energy supply of Echinococcus granulosus. It's like disrupting the flow of desert winds that provide life to a sandstorm. The researchers found that mebendazole reduced the glucose and glycogen content in the parasite's cyst wall, potentially weakening its ability to thrive in the host's body.

Combating Parasitic Infections

Parasitic infections, like persistent desert sandstorms, can cause various health problems. Finding effective treatments is crucial for managing these infections and restoring health. This study contributes to our understanding of how mebendazole works against parasites, providing valuable insights for developing more effective anti-parasitic therapies.

Dr. Camel's Conclusion

This study explores the potential of mebendazole in combating Echinococcus granulosus infections. It's like a resourceful desert explorer finding a way to disrupt the flow of a sandstorm, limiting its destructive power. This research offers valuable insights into the mechanisms of mebendazole's action, paving the way for future investigations into more effective strategies for combating parasitic infections.
Date :
  1. Date Completed 1993-06-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8503286

DOI: Digital Object Identifier

8503286

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PICO Info
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Languages

Chinese

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