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Comparison of photochemotherapy and dithranol in the treatment of chronic plaque psoriasis.

Author: BriffaD V, GreavesM, MarksJ, RogersS, ShusterS, WarinA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

P.U.V.A. treatment was more effective than dithranol in clearing psoriasis lesions, but took longer. P.U.V.A. was more convenient and acceptable to patients, and could be used for patients who failed dithranol or required methotrexate.
Paper Details　
Original Abstract of the Article :
A two-centre trial has been carried out on 224 patients with chronic plaque psoriasis randomly allocated to treatment with a standard dithranol regimen of 8-methoxypsoralen and long-wave ultraviolet light (P.U.V.A.). Lesions in 91% of the 113 in the P.U.V.A. group cleared satisfactorily compared wit...See full text at original site
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引用元：
https://doi.org/10.1016/s0140-6736(79)90820-1

データ提供：米国国立医学図書館（NLM）

Photochemotherapy vs. Dithranol for Psoriasis: A Camel's Tale of Two Treatments

This research delves into the world of psoriasis, a skin condition as persistent as a desert sand dune. The study compares two treatments, photochemotherapy (PUVA) and dithranol, for chronic plaque psoriasis. Researchers randomly assigned 224 patients to receive one of these treatments. They found that PUVA cleared lesions in 91% of patients, while dithranol cleared lesions in 82%. However, PUVA took longer to achieve clearance. Despite the longer treatment time, PUVA was found to be more convenient and acceptable to patients. This study provides valuable insights into the effectiveness and patient preferences for these two treatment options.

PUVA: A Light at the End of the Psoriasis Tunnel

The study highlights the effectiveness of PUVA, a treatment that utilizes light therapy, in clearing psoriasis lesions. Although PUVA takes longer than dithranol, its convenience and patient acceptability make it a promising option for those seeking relief from the persistent symptoms of psoriasis. The study's findings suggest that PUVA can be a more appealing alternative for patients, especially those who struggle with the challenges of traditional treatments.

Camel's Perspective: Finding the Coolest Shade

Navigating the scorching heat of psoriasis requires finding the right shade. PUVA offers a more convenient approach than dithranol, making it a welcome oasis for patients seeking relief. It's like finding the coolest spot under a towering acacia tree in the desert.

Dr.Camel's Conclusion

This study sheds light on the benefits of PUVA in treating chronic plaque psoriasis. While PUVA requires a longer treatment period than dithranol, its convenience and patient acceptability make it a valuable option. The findings suggest that PUVA may be particularly well-suited for patients who are seeking a less disruptive and more comfortable approach to psoriasis management.

Date :
  1. Date Completed 1979-05-23
  2. Date Revised 2019-06-10
Further Info :

Pubmed ID

85052

DOI: Digital Object Identifier

10.1016/s0140-6736(79)90820-1

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・Effective treatment of psoriasis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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