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Skin side-effects of amiodarone therapy.

Author: EttlerK, GregorJ, Nozi ckováM, PidrmanV, SubrtováD

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Amiodarone, an antiarrhythmic drug, induced photosensitivity and greyish-blue hyperpigmentation in 9.4% of patients in a study. Histological examination confirmed these findings.
Paper Details　
Original Abstract of the Article :
Amiodarone is a antiarrhythmic drug with many side-effects which include also the induction of photosensitivity and the development of greyish-blue pigmentations on the skin exposed to light. The authors examined 64 patients treated with amiodarone and 32 controls by means of a phototest using a xen...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8599073

データ提供：米国国立医学図書館（NLM）

Amiodarone: A Journey Through the Desert of Side Effects

Amiodarone, a potent antiarrhythmic medication used to treat heart rhythm disorders, is known for its diverse range of side effects, including photosensitivity and skin pigmentation. This study delves into the skin side effects of amiodarone therapy, specifically examining the development of greyish-blue pigmentation on sun-exposed skin.

Amiodarone: Unveiling the Skin Side Effects

The researchers conducted a phototest on 64 patients receiving amiodarone therapy and 32 controls. They found that approximately 10% of patients receiving amiodarone developed photosensitivity and greyish-blue hyperpigmentation, primarily on the face and back of the hands. This study underscores the importance of being aware of these potential skin side effects in patients receiving amiodarone therapy. The researchers also conducted histological and electron microscopic examination of the hyperpigmentation, further characterizing this side effect.

Amiodarone: Navigating the Desert of Potential Side Effects

This research highlights the importance of understanding and managing the potential side effects of medications, even those with significant therapeutic benefits. The study's findings emphasize the need for careful monitoring of patients receiving amiodarone therapy, particularly regarding skin side effects. Healthcare professionals should educate patients about the potential for photosensitivity and hyperpigmentation, advising them to protect their skin from sun exposure and to report any unusual skin changes promptly. This research serves as a reminder to navigate the desert of potential side effects with vigilance and patient-centered care.

Dr.Camel's Conclusion

Amiodarone, a valuable antiarrhythmic medication, can cause photosensitivity and greyish-blue hyperpigmentation on sun-exposed skin. This study underscores the importance of being aware of these potential side effects and educating patients about appropriate skin protection measures. This research reminds us to navigate the desert of medication side effects with vigilance and patient-centered care, ensuring patient safety and well-being.
Date :
  1. Date Completed 1996-04-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8599073

DOI: Digital Object Identifier

8599073

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Article Analysis
・Side Effects of amiodarone
SNS
PICO Info
in preparation
Languages

English

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