Randomised controlled trial of methyldopa and isradipine in preeclampsia--effects on uteroplacental and fetal hemodynamics.

Author: AnandakumarC, ArulkumaranS, IngemarssonI, MontanS, RatnamS

Paper Details 
Original Abstract of the Article :
This is a prospective randomised controlled study in 21 women admitted with preeclampsia in the third trimester. The mean arterial blood pressure decreased by 11.1 mmHg (95% confidence interval -14.9 to -7.3 mmHg) in the methyldopa group, and by 9.3 mmHG (95% confidence interval-14.4 to -4.2 mmHG) i...See full text at original site
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引用元:
https://doi.org/10.1515/jpme.1996.24.2.177

データ提供:米国国立医学図書館(NLM)

Managing Preeclampsia: A Comparison of Methyldopa and Isradipine

Preeclampsia, a pregnancy complication that can be as unpredictable as a desert sandstorm, requires careful management. This study compares the effectiveness of two medications, methyldopa and isradipine, in treating preeclampsia. Think of these medications as two different camel caravans, each equipped to navigate the challenging terrain of pregnancy complications.

Similar Hypotensive Effects: A Safe Passage Through the Desert

The researchers found that both methyldopa and isradipine effectively lower blood pressure in preeclamptic patients. Both caravans are able to successfully navigate the difficult terrain of pregnancy complications, providing a safe passage for both the mother and the developing baby. The study also notes that both medications have minimal impact on fetal and uteroplacental hemodynamics, suggesting that they are relatively safe for the developing baby.

Choosing the Right Medication: A Personalized Approach

This study highlights the importance of individualized treatment for preeclampsia, like choosing the caravan that's best suited for the specific challenges of the desert. While both medications effectively lower blood pressure, choosing the right one may depend on factors like individual tolerance and potential side effects.

Dr.Camel's Conclusion

This research provides valuable insights into the management of preeclampsia, showcasing the effectiveness of methyldopa and isradipine in lowering blood pressure. It's like having two different but equally skilled caravans, each equipped to navigate the challenging terrain of pregnancy complications safely and effectively. Choosing the right caravan for the journey is a collaborative decision between the patient and their healthcare provider.

Date :
  1. Date Completed 1996-11-12
  2. Date Revised 2019-09-20
Further Info :

Pubmed ID

8773944

DOI: Digital Object Identifier

10.1515/jpme.1996.24.2.177

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English

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