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[Intravitreal injection of ganciclovir in AIDS patients with cytomegalovirus retinitis].

Author: FujinoY, IwamotoA, KimuraS, MiyoshiM, MochizukiM, NagataY, OkaS, OnoA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the therapeutic effects and safety of intravitreal ganciclovir injection in patients with cytomegalovirus (CMV) retinitis. Intravitreal ganciclovir injections were effective in suppressing CMV retinitis, but serious complications such as endophthalmitis and retinal detachment were observed.
Paper Details　
Original Abstract of the Article :
The therapeutic effects and safety of intravitreal ganciclovir injection were evaluated in 16 acquired immunodeficiency syndrome (AIDS) patients with cytomegalovirus (CMV) retinitis. The induction therapy was done in a total of 23 courses, i.e., in 14 eyes of 10 patients. Active lesions of CMV retin...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8810241

データ提供：米国国立医学図書館（NLM）

Intravitreal Ganciclovir: A Treatment for CMV Retinitis in AIDS Patients

Cytomegalovirus (CMV) retinitis is a serious eye infection that can occur in individuals with AIDS. This study evaluates the effectiveness and safety of intravitreal ganciclovir injection, a treatment option for this condition. The authors examined the treatment outcomes in 16 AIDS patients with CMV retinitis, providing valuable insights into the efficacy and potential complications of this approach.

Intravitreal Ganciclovir: A Potential Treatment Option

The study highlights the potential of intravitreal ganciclovir injection as a viable treatment option for CMV retinitis in AIDS patients. While the treatment demonstrated efficacy in suppressing active lesions and preventing reactivation, the authors acknowledge the presence of serious complications, including endophthalmitis and retinal detachment. They emphasize the importance of careful procedures and ongoing monitoring to ensure patient safety and maximize treatment benefits.

Navigating the Terrain of Infectious Diseases

Imagine a camel traversing a desert landscape, encountering unexpected obstacles and hazards. Similarly, healthcare professionals must navigate the complex terrain of infectious diseases, carefully choosing treatment options and managing potential complications. This study sheds light on the effectiveness and potential risks of intravitreal ganciclovir injection for CMV retinitis in AIDS patients, offering valuable insights for clinicians managing this challenging condition.

Dr. Camel's Conclusion

This study explores the use of intravitreal ganciclovir injection for CMV retinitis in AIDS patients. While offering potential benefits, the treatment also carries inherent risks. This research underscores the importance of careful consideration, thorough monitoring, and a comprehensive understanding of treatment options and potential complications when managing infectious diseases, particularly in vulnerable populations.
Date :
  1. Date Completed 1996-12-11
  2. Date Revised 2015-10-08
Further Info :

Pubmed ID

8810241

DOI: Digital Object Identifier

8810241

Related Literature

Article Analysis
・Effects of ganciclovir injection
SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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