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[Effectiveness and tolerance of benazepril versus captopril in patients with hypertension].

Author: GolubevS A, MorozovaT E, Ol'binskaiaL I

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study compared the antihypertensive efficacy and tolerance of benazepril and captopril in patients with mild to moderate hypertension. Benazepril and captopril were effective and well-tolerated, with a low incidence of side effects.
Paper Details　
Original Abstract of the Article :
A double blind placebo-controlled trial was performed to evaluate antihypertension efficacy and tolerance of a new inhibitor of angiotensin-converting enzyme benazepril (a single daily dose 10-20 mg) versus captopril (50 mg 1-2 times daily) in 30 patients with mild and moderate hypertension. Monothe...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8815273

データ提供：米国国立医学図書館（NLM）

Benazepril vs. Captopril: A Tale of Two ACE Inhibitors

The battle against hypertension is a continuous quest for effective and well-tolerated medications. This research delves into the world of angiotensin-converting enzyme (ACE) inhibitors, exploring the efficacy and tolerability of benazepril compared to captopril in patients with mild to moderate hypertension. The study used a double-blind, placebo-controlled trial to compare the effects of these two drugs.

Benazepril: An Effective and Well-Tolerated Option

The study found that benazepril achieved an antihypertensive efficacy of 71%, while captopril achieved 64%. Furthermore, benazepril was well-tolerated, with only two patients experiencing side effects, compared to one patient in the captopril group.

ACE Inhibitors: A Vital Weapon in the Fight Against Hypertension

This research demonstrates that benazepril, a single-daily dose ACE inhibitor, offers an effective and well-tolerated treatment option for hypertension. While further research is needed to explore its long-term effects, it offers a promising addition to the arsenal against high blood pressure.

Dr. Camel's Conclusion

The study shows that when it comes to controlling hypertension, benazepril is a reliable camel that can carry us through the desert of high blood pressure! It offers a good balance between efficacy and tolerability, making it a viable option for patients seeking relief from hypertension.

Date :
  1. Date Completed 1996-10-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8815273

DOI: Digital Object Identifier

8815273

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Languages

Russian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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