Metabolic alkalosis and myoclonus from antacid ingestion.

Author: KobayashiS, KonoN, OkadaK, YamaguchiS

Paper Details 
Original Abstract of the Article :
A patient with a history of cerebrovascular disease, hypertension, and previous gastrectomy developed metabolic alkalosis and myoclonus. His medications included the anti-hypertensive agents nicardipine hydrochloride, delapril, prazosin; dihydroergotoxin and ticlopidine for cerebral infarction; esta...See full text at original site
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引用元:
https://doi.org/10.2169/internalmedicine.35.515

データ提供:米国国立医学図書館(NLM)

Metabolic Alkalosis and Myoclonus: An Unexpected Side Effect

Metabolic alkalosis, a condition characterized by an imbalance in blood pH, can be caused by a variety of factors. This case report describes a patient who developed metabolic alkalosis and myoclonus, involuntary muscle spasms, after ingesting high doses of an antacid containing sodium bicarbonate. The authors investigate the potential link between the antacid and the patient's symptoms.

Antacids: Potential for Adverse Effects

The study's findings highlight the potential for adverse effects, even from commonly used medications like antacids. The authors emphasize the importance of considering the potential for drug interactions and unintended consequences when prescribing or using medications, particularly when high doses are involved. This case report underscores the need for careful monitoring and assessment of patient symptoms, even with seemingly benign medications.

Taking a Holistic Approach to Health

This case report reminds us that health is a complex interplay of various factors. While the patient's symptoms were initially attributed to his underlying conditions, the investigation revealed the crucial role of antacid ingestion. This study emphasizes the need for a holistic approach to health, considering the interplay of medications, lifestyle factors, and individual susceptibility to adverse effects.

Dr. Camel's Conclusion

Just as a camel can become dehydrated in a desert environment, excessive intake of antacids can lead to metabolic imbalances. This case study highlights the importance of being mindful of potential side effects, even with commonly used medications. By understanding the complexities of drug interactions and individual responses, we can navigate the terrain of medication management with greater awareness and safety.

Date :
  1. Date Completed 1997-02-04
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

8835608

DOI: Digital Object Identifier

10.2169/internalmedicine.35.515

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