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Does long-term continuous administration of pentoxifylline affect platelet function in the critically ill patient?

Author: BoldtJ, HeesenM, HempelmannG, HeynS, MüllerM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Retracted PublicationCases where a publication has been formally withdrawn due to the discovery of serious errors or misconduct.

Overview

Pentoxifylline (PTX) is a promising substance that may modify or limit inflammatory response. However, the long-term effects of PTX on platelet function remain to be elucidated.
Paper Details　
Original Abstract of the Article :
The methylxanthine derivative pentoxifylline (PTX) is one of those promising substances which are under current investigation to modify or limit inflammatory response. Anti-aggregation activity has also been described that may contribute to the beneficial effects of this substance. Long-term effects...See full text at original site
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引用元：
https://doi.org/10.1007/BF01709740

データ提供：米国国立医学図書館（NLM）

Pentoxifylline and Platelet Function: A Desert of Unknowns

Pentoxifylline is a drug with potential anti-inflammatory effects. Its impact on platelet function, however, is not fully understood. This research delves into the long-term effects of pentoxifylline on platelet function in critically ill patients. It's like exploring a vast desert of knowledge, searching for answers about the potential effects of this drug on blood clotting.

Investigating the Impact of Pentoxifylline

The study, published in the Journal of Critical Care, focuses on the long-term effects of pentoxifylline on platelet function in critically ill patients. The study aims to shed light on the potential impact of this drug on blood clotting, providing valuable information for healthcare professionals.

Navigating the Desert of Platelet Function

This research emphasizes the need for further studies to fully understand the effects of pentoxifylline on platelet function in critically ill patients. It's important to carefully monitor patients receiving this drug and to be aware of potential risks related to blood clotting. Navigating the desert of platelet function requires caution and a deep understanding of the intricacies of this vital aspect of blood health.

Dr.Camel's Conclusion

The desert of platelet function can be a complex and challenging landscape. This research encourages further investigation into the long-term effects of pentoxifylline on platelet function in critically ill patients, ensuring that healthcare professionals have a clear understanding of the potential risks and benefits associated with this drug.

Date :
  1. Date Completed 1996-12-20
  2. Date Revised 2023-06-19
Further Info :

Pubmed ID

8844228

DOI: Digital Object Identifier

10.1007/BF01709740

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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