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Quinupristin/dalfopristin (RP 59500): a new streptogramin antibiotic.

Author: ChantC, RybakM J

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

RP 59500 may be an alternative to the glycopeptides, especially for inherently resistant organisms. Further studies are needed to confirm its activity and to establish its clinical efficacy.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To review the current knowledge on RP 59500 (quinupristin/dalfopristin, Synercid), a new streptogramin antibiotic, with respect to its pharmacology, pharmacokinetics, pharmacodynamics, mechanism of resistance, and in vitro inhibitory and bactericidal activity. DATA SOURCES: A MEDLINE sea...See full text at original site
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引用元：
https://doi.org/10.1177/106002809502901013

データ提供：米国国立医学図書館（NLM）

Quinupristin/Dalfopristin: A New Antibiotic with Promise

This study examines quinupristin/dalfopristin, a new antibiotic belonging to the streptogramin class. The researchers explored its properties, including its effectiveness against various bacteria, how it works, and its potential side effects. They also investigated its ability to overcome resistance, a growing challenge in the fight against bacterial infections.

The findings revealed that quinupristin/dalfopristin demonstrated activity against many gram-positive bacteria, including some strains that are resistant to other antibiotics, such as vancomycin-resistant Enterococcus faecium. This is like finding a new oasis in a desert where other water sources have dried up. It offers a potential solution to combat antibiotic resistance.

New Hope in the Fight Against Antibiotic Resistance

This study provides a glimmer of hope in the fight against antibiotic resistance. Quinupristin/dalfopristin's effectiveness against resistant bacteria suggests that it could be a valuable tool in treating infections that are difficult to manage with existing antibiotics.

Understanding Antibiotic Resistance

Antibiotic resistance is a growing global health threat. It's crucial to use antibiotics appropriately and to support research efforts to develop new antibiotics to combat this challenge.

Dr.Camel's Conclusion

This research explores the potential of a new antibiotic, quinupristin/dalfopristin, in combating antibiotic resistance. Like a camel finding a new water source in a parched desert, this research offers a potential solution to a critical medical challenge. The study underscores the ongoing need for research and development in the fight against antibiotic resistance.

Date :
  1. Date Completed 1996-10-24
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

8845540

DOI: Digital Object Identifier

10.1177/106002809502901013

SNS
PICO Info
in preparation
Languages

English

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