Sodium polystyrene sulfonate treatment for lithium toxicity: effects on serum potassium concentrations.

Author: HullK M, LacoutureP G, LewanderW J, LinakisJ G, LockhartG R, MaherT J

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To examine the effects of sodium polystyrene sulfonate (SPS) on serum potassium (K) concentrations in mice pretreated with parenteral lithium (Li). METHODS: A placebo-controlled murine model trial of SPS therapy following IV Li was performed. Sixty male CD-1 mice weighing 18-22 g were ad...See full text at original site
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引用元:
https://doi.org/10.1111/j.1553-2712.1996.tb03446.x

データ提供:米国国立医学図書館(NLM)

The Unexpected Twist: Sodium Polystyrene Sulfonate and Its Impact on Potassium Levels

The treatment of [lithium toxicity], a serious condition that can arise from high levels of lithium in the body, often involves the use of [sodium polystyrene sulfonate (SPS)]. This study investigates the potential impact of SPS on [serum potassium (K) concentrations] in mice treated with [lithium (Li)]. The researchers observed a significant reduction in [serum K concentrations] in animals treated with SPS, regardless of whether they received lithium or saline. These findings highlight the potential risk of [hypokalemia], a condition characterized by low potassium levels, associated with SPS treatment. The study emphasizes the importance of carefully monitoring [serum K levels] in patients receiving SPS therapy for lithium toxicity. This research contributes to our understanding of the potential risks and benefits of SPS treatment for lithium toxicity.

SPS's Hidden Effect: Navigating the Desert of Electrolyte Balance

The study's findings highlight the need for caution when using SPS to treat [lithium toxicity] due to its potential to induce [hypokalemia]. Imagine a desert traveler venturing through a vast expanse, relying on a seemingly reliable source of water. However, this source may contain hidden impurities, leading to unforeseen consequences. Similarly, SPS, while effective in treating [lithium toxicity], can also disrupt [electrolyte balance], leading to [hypokalemia]. This research emphasizes the importance of careful monitoring and understanding the potential side effects of medications.

A Desert Oasis with Unexpected Twists: The Complexities of Lithium Toxicity Treatment

The study's findings underscore the importance of understanding the full spectrum of effects associated with medications. Imagine a desert traveler seeking refuge in an oasis, only to discover hidden dangers lurking beneath the surface. Similarly, SPS, while offering a lifeline for [lithium toxicity], can also have unexpected consequences, such as [hypokalemia]. This research emphasizes the need for careful monitoring and personalized treatment approaches to manage the complexities of [lithium toxicity].

Dr.Camel's Conclusion

This study highlights the potential risk of [hypokalemia] associated with SPS treatment for [lithium toxicity]. Careful monitoring of [serum K levels] is crucial for patients receiving SPS therapy to ensure safe and effective management of [lithium toxicity].

Date :
  1. Date Completed 1996-12-11
  2. Date Revised 2019-09-09
Further Info :

Pubmed ID

8881542

DOI: Digital Object Identifier

10.1111/j.1553-2712.1996.tb03446.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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