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Comparative evaluation of efficacy and safety of ciprofloxacin and norfloxacin ophthalmic solutions.

Author: AdenisJ P, BrasseurG, ColinJ, DemaillyP, MaletF, OlléP, RetoutA, Saint-BlancatP, VerinP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Ciprofloxacin and norfloxacin ophthalmic solutions were equally effective and well-tolerated in the treatment of bacterial conjunctivitis and blepharitis. Both treatments resulted in clinical cure or improvement in 96% of patients.
Paper Details　
Original Abstract of the Article :
The efficacy and safety of ciprofloxacin ophthalmic solution 0.3% and norfloxacin ophthalmic solution 0.3% in the treatment of bacterial conjunctivitis and blepharitis were compared in a double masked randomised study. A total of 131 patients, 65 treated with ciprofloxacin (42 with conjunctivitis an...See full text at original site
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引用元：
https://doi.org/10.1177/112067219600600312

データ提供：米国国立医学図書館（NLM）

Comparing Ciprofloxacin and Norfloxacin for Bacterial Conjunctivitis and Blepharitis

In the field of [ophthalmology], [bacterial conjunctivitis and blepharitis] are common conditions that require effective treatment. This study compares the [efficacy and safety] of [ciprofloxacin and norfloxacin ophthalmic solutions] in treating these conditions. The researchers conducted a [double-masked randomized study] involving [131 patients] with [bacterial conjunctivitis or blepharitis], comparing the [clinical outcomes and adverse events] associated with each medication.

Ciprofloxacin and Norfloxacin: Similar Efficacy and Safety

The results indicate that [ciprofloxacin and norfloxacin ophthalmic solutions] are [equally effective and safe] in treating [bacterial conjunctivitis and blepharitis]. Both medications achieved [similar rates of pathogen eradication and clinical cure] and were [well-tolerated] by patients. The study found no significant differences between the two treatments in terms of [clinical improvement or adverse events].

Effective Treatment Options for Conjunctivitis and Blepharitis

This research provides valuable information for [ophthalmologists] treating [bacterial conjunctivitis and blepharitis]. It suggests that both [ciprofloxacin and norfloxacin ophthalmic solutions] are [safe and effective treatment options], offering [comparable outcomes] for patients. This study highlights the importance of [individualized treatment decisions] based on [patient factors and the specific type of infection].

Dr.Camel's Conclusion

This study is a clear oasis of knowledge in the often-irritating landscape of [bacterial conjunctivitis and blepharitis]. The findings show that both [ciprofloxacin and norfloxacin ophthalmic solutions] offer [effective and well-tolerated] treatment options, giving [ophthalmologists] valuable tools for managing these common conditions.

Date :
  1. Date Completed 1997-02-06
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

8908436

DOI: Digital Object Identifier

10.1177/112067219600600312

Related Literature

Article Analysis
・Effects of ciprofloxacin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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