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Biochemical changes during a cross-over treatment of doxazosin, moduretic and amlodipine in hypertensive patients.
Author: AgbedanaE O, AhanekuJ E, SalakoL A, SowunmiA, TaylorG O, WalkerO
Original Abstract of the Article :
A cross-over study was done to compare the effects of doxazosin, moduretic and amlodipine on biochemical values in 9 hypertensive Nigerians aged 35 to 65 years. Doxazosin therapy was characterized by significant increase in the levels of mean plasma total protein and albumin, while moduretic therapy...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8991356
データ提供:米国国立医学図書館(NLM)
Comparing Antihypertensive Therapies: Doxazosin, Moduretic, and Amlodipine
The field of [Cardiology] is constantly seeking effective and safe treatments for [Hypertension], a major public health concern. This study investigates the effects of three different antihypertensive medications—[Doxazosin], [Moduretic], and [Amlodipine]—on [Biochemical Values] in [Hypertensive Patients]. The researchers conducted a [Cross-Over Study] involving [Hypertensive Nigerians] to compare the impact of these drugs on [Plasma Total Protein], [Albumin], [Plasma Creatinine], and [Calcium]. Their findings reveal that [Doxazosin] significantly increased [Plasma Total Protein] and [Albumin] levels, while [Moduretic] led to a significant reduction in [Plasma Creatinine] and [Calcium] levels. [Amlodipine] had no significant effect on the studied biochemical parameters. This research provides valuable insights into the biochemical profiles associated with different antihypertensive therapies and underscores the importance of considering individual patient factors in treatment selection.
Tailoring Treatment for Optimal Outcomes
The study's findings highlight the importance of personalized treatment approaches in managing [Hypertension]. The observed differences in [Biochemical Values] among patients taking different medications underscore the need for careful consideration of individual factors, such as pre-existing conditions and potential drug interactions, in determining the most appropriate therapy. This emphasizes the importance of a collaborative approach between healthcare providers and patients in navigating the diverse landscape of antihypertensive medications.
Navigating the World of Antihypertensive Therapies
The study's findings contribute to our understanding of the [Biochemical Effects] of different antihypertensive medications. This knowledge can inform healthcare professionals in selecting the most appropriate therapy for individual patients, taking into account their unique characteristics and potential risks. Just as a desert traveler navigates diverse landscapes, we must approach the selection of antihypertensive medications with careful consideration and a commitment to personalized care.
Dr.Camel's Conclusion
This research underscores the importance of understanding the intricate interplay between [Pharmaceuticals] and [Biochemical Processes] within the body. Like a desert ecosystem where every species plays a vital role, each medication interacts with the body in a unique way. This study serves as a reminder that the pursuit of optimal health requires a personalized approach to treatment and a deep understanding of the complex mechanisms at play.
Date :
- Date Completed 1997-02-04
- Date Revised 2013-11-21
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English
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