Biochemical changes during a cross-over treatment of doxazosin, moduretic and amlodipine in hypertensive patients.

Author: AgbedanaE O, AhanekuJ E, SalakoL A, SowunmiA, TaylorG O, WalkerO

Paper Details 
Original Abstract of the Article :
A cross-over study was done to compare the effects of doxazosin, moduretic and amlodipine on biochemical values in 9 hypertensive Nigerians aged 35 to 65 years. Doxazosin therapy was characterized by significant increase in the levels of mean plasma total protein and albumin, while moduretic therapy...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/8991356

データ提供:米国国立医学図書館(NLM)

Comparing Antihypertensive Therapies: Doxazosin, Moduretic, and Amlodipine

The field of [Cardiology] is constantly seeking effective and safe treatments for [Hypertension], a major public health concern. This study investigates the effects of three different antihypertensive medications—[Doxazosin], [Moduretic], and [Amlodipine]—on [Biochemical Values] in [Hypertensive Patients]. The researchers conducted a [Cross-Over Study] involving [Hypertensive Nigerians] to compare the impact of these drugs on [Plasma Total Protein], [Albumin], [Plasma Creatinine], and [Calcium]. Their findings reveal that [Doxazosin] significantly increased [Plasma Total Protein] and [Albumin] levels, while [Moduretic] led to a significant reduction in [Plasma Creatinine] and [Calcium] levels. [Amlodipine] had no significant effect on the studied biochemical parameters. This research provides valuable insights into the biochemical profiles associated with different antihypertensive therapies and underscores the importance of considering individual patient factors in treatment selection.

Tailoring Treatment for Optimal Outcomes

The study's findings highlight the importance of personalized treatment approaches in managing [Hypertension]. The observed differences in [Biochemical Values] among patients taking different medications underscore the need for careful consideration of individual factors, such as pre-existing conditions and potential drug interactions, in determining the most appropriate therapy. This emphasizes the importance of a collaborative approach between healthcare providers and patients in navigating the diverse landscape of antihypertensive medications.

Navigating the World of Antihypertensive Therapies

The study's findings contribute to our understanding of the [Biochemical Effects] of different antihypertensive medications. This knowledge can inform healthcare professionals in selecting the most appropriate therapy for individual patients, taking into account their unique characteristics and potential risks. Just as a desert traveler navigates diverse landscapes, we must approach the selection of antihypertensive medications with careful consideration and a commitment to personalized care.

Dr.Camel's Conclusion

This research underscores the importance of understanding the intricate interplay between [Pharmaceuticals] and [Biochemical Processes] within the body. Like a desert ecosystem where every species plays a vital role, each medication interacts with the body in a unique way. This study serves as a reminder that the pursuit of optimal health requires a personalized approach to treatment and a deep understanding of the complex mechanisms at play.

Date :
  1. Date Completed 1997-02-04
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8991356

DOI: Digital Object Identifier

4358

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.