Pseudoephedrine is without ergogenic effects during prolonged exercise.

Author: DermanW E, EvansA, GabrielsG, GilliesH, NoakesT D, SmithP

Paper Details 
Original Abstract of the Article :
This study was designed to measure whether a single dose of 120 mg pseudoephedrine ingested 120 min before exercise influences performance during 1 h of high-intensity exercise. The effects of exercise on urinary excretion of the drug were also studied. Ten healthy male cyclists were tested on two o...See full text at original site
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引用元:
https://doi.org/10.1152/jappl.1996.81.6.2611

データ提供:米国国立医学図書館(NLM)

Pseudoephedrine: No Ergogenic Effects During Prolonged Exercise

This study investigates the ergogenic effects of pseudoephedrine, a common decongestant, on exercise performance during prolonged high-intensity exercise. The researchers conducted a double-blind, placebo-controlled, crossover study involving 10 healthy male cyclists, who performed a 1-hour high-intensity exercise trial after ingesting either a single dose of 120 mg pseudoephedrine or a placebo. Their findings revealed no significant difference in time trial performance or isometric muscle function between the pseudoephedrine and placebo groups. Furthermore, the study demonstrated that exercise significantly increased urinary pseudoephedrine excretion and plasma concentrations in most subjects, but not in all. These findings suggest that a single therapeutic dose of pseudoephedrine does not enhance exercise performance during prolonged high-intensity exercise and may even be affected by exercise itself.

A Reality Check for Ergogenic Aids: Pseudoephedrine Falls Short

This study provides compelling evidence that pseudoephedrine, a commonly used decongestant, does not possess ergogenic effects during prolonged high-intensity exercise. The findings dispel any potential misconceptions about pseudoephedrine's ability to enhance athletic performance. This research underscores the importance of evidence-based decision-making in the context of ergogenic aids, emphasizing the need for rigorous scientific investigation to evaluate potential performance-enhancing substances.

Navigating the Desert of Performance Enhancement: A Search for Truth

As a researcher, I am committed to seeking the truth behind claims of performance-enhancing substances. This study serves as a reminder that the desert of sports science is often filled with mirages and misleading promises. The journey toward understanding true ergogenic effects requires a persistent search for evidence-based findings, rejecting anecdotal claims and unsubstantiated hype. This study reinforces the importance of scientific rigor in evaluating potential performance-enhancing substances, ensuring that athletes can rely on sound scientific data to guide their training and performance.

Dr.Camel's Conclusion

This study provides evidence that a single therapeutic dose of pseudoephedrine does not enhance exercise performance during prolonged high-intensity exercise. The findings highlight the importance of evidence-based decision-making in evaluating potential ergogenic aids and suggest that exercise can significantly alter the pharmacokinetics of pseudoephedrine.

Date :
  1. Date Completed 1997-04-09
  2. Date Revised 2017-12-13
Further Info :

Pubmed ID

9018513

DOI: Digital Object Identifier

10.1152/jappl.1996.81.6.2611

Related Literature

SNS
PICO Info
in preparation
Languages

English

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