Antivirals for pandemic influenza.

Author: HaydenF G

Paper Details 
Original Abstract of the Article :
Amantadine and rimantadine share features that would make them useful agents in responding to pandemic influenza. These include an antiviral spectrum encompassing influenza A viruses, favorable pharmacokinetics, a potential for stockpiling supplies, and documented prophylactic and therapeutic effect...See full text at original site
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引用元:
https://doi.org/10.1086/514177

データ提供:米国国立医学図書館(NLM)

Antivirals for Pandemic Influenza: A Balancing Act of Benefits and Risks

Pandemic influenza poses a significant public health threat, requiring effective antiviral strategies. This study examines the potential role of amantadine and rimantadine, two antiviral drugs, in responding to a pandemic influenza outbreak. The authors discuss the advantages of these drugs, including their antiviral spectrum, favorable pharmacokinetics, stockpiling potential, and documented prophylactic and therapeutic effectiveness. However, they also highlight the challenges associated with their use, such as insufficient production capacity, potential for adverse drug effects, and the emergence of drug-resistant viruses. The authors also discuss the promise of neuraminidase inhibitors but emphasize the need for further research to address issues related to prophylactic efficacy, cost, administration, and resistance emergence.

Antivirals: A Complex Approach to Pandemic Influenza

The study reveals the complexities of using antivirals to combat pandemic influenza. While amantadine and rimantadine offer potential benefits, their limitations must be carefully considered. The emergence of drug-resistant viruses highlights the importance of ongoing research to develop new antiviral therapies.

Antivirals: Navigating the Uncertainties of Pandemic Influenza

Pandemic influenza underscores the importance of preparedness and ongoing research in the face of emerging health threats. This study provides valuable insights into the potential role of antivirals in pandemic influenza response, highlighting the need for a balanced approach that considers both benefits and risks.

Dr.Camel's Conclusion

This study provides a comprehensive overview of the current landscape of antiviral medications for pandemic influenza. The authors skillfully balance the potential benefits and limitations of these drugs, offering valuable insights for public health professionals and researchers.

Date :
  1. Date Completed 1997-08-14
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

9240696

DOI: Digital Object Identifier

10.1086/514177

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PICO Info
in preparation
Languages

English

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