Paper Details 
Original Abstract of the Article :
The effects of penbutolol (Hoe 893 d), a new non-selective beta-receptor blocking agent, were studied in 5 patients with moderate hypertension. Initially, it was shown that 2-4 mg given orally once or twice daily tended to lower blood pressure and pulse rate, both at rest and following submaximal wo...See full text at original site
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引用元:
https://doi.org/10.1007/BF00613424

データ提供:米国国立医学図書館(NLM)

Penbutolol: A Long-Term Journey in the Desert of Hypertension

Hypertension, or high blood pressure, is a silent but powerful sandstorm in the circulatory system. This study investigates the long-term effects of penbutolol, a beta-blocker, on patients with moderate hypertension. Researchers followed 5 patients for 3 to 8 months, monitoring their blood pressure, pulse rate, and hormone levels under various conditions.

The study found that penbutolol effectively lowered blood pressure and pulse rate in these patients. It's like a cooling oasis in the desert of high blood pressure. Penbutolol also had a significant impact on hormone levels. For example, it inhibited the production of renin, a hormone involved in regulating blood pressure, and lowered the levels of aldosterone, a hormone that helps control blood pressure and electrolyte balance. This is like a carefully crafted irrigation system, managing the flow of water (hormones) to maintain a healthy balance.

A Promising Long-Term Treatment for Hypertension

These findings suggest that penbutolol might be a valuable tool for managing moderate hypertension over the long term. However, it's important to remember that everyone is different, and it's crucial to discuss penbutolol with a healthcare professional to determine if it's right for you.

Staying Hydrated in the Desert of Hypertension

Managing hypertension is a lifelong journey. It's important to maintain a healthy lifestyle, including regular exercise, a balanced diet, and stress management. These strategies can help keep your blood pressure in check, like a well-maintained irrigation system ensuring a healthy flow of water.

Dr.Camel's Conclusion

This study sheds light on the potential of penbutolol as a long-term treatment for moderate hypertension. It's a reminder that even in the challenging desert of chronic conditions, there are often options for managing symptoms and improving quality of life.

Date :
  1. Date Completed 1976-11-21
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

9298

DOI: Digital Object Identifier

10.1007/BF00613424

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Languages

English

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