A double-blind, multicentre, placebo-controlled study of tiludronate in Paget's disease of bone.

Author: CreekR A, FraserW D, PicotC, SawyerJ P, StampT C

Paper Details 
Original Abstract of the Article :
A multicentre, randomised, placebo-controlled, dose-ranging study was conducted to investigate the therapeutic activity and sustained efficacy of tiludronate (200 mg, 400 mg and 600 mg once daily) taken orally for 12 weeks in patients with Paget's disease. Serum alkaline phosphatase concentrations w...See full text at original site
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引用元:
https://doi.org/10.1136/pgmj.73.862.496

データ提供:米国国立医学図書館(NLM)

Tiludronate: A New Oasis in the Desert of Paget's Disease

[Paget's disease of bone] is a chronic condition that affects the skeletal system. This study investigates the effectiveness of [tiludronate] as a treatment for [Paget's disease]. The authors conducted a [double-blind, placebo-controlled trial] to compare the efficacy of [tiludronate] to [placebo]. Their findings demonstrate that [tiludronate] is a [promising therapeutic option] for [Paget's disease] and that [dose-response] was observed.

Navigating the Desert of Paget's Disease: Tiludronate as a Potential Remedy

Imagine a [desert landscape] where the [bones] are [brittle and fragile]. [Paget's disease] is like a [storm] that ravages the [skeletal system]. This research reveals a potential [oasis of relief] in the form of [tiludronate]. The study demonstrates that [tiludronate] is [effective in treating Paget's disease] and that a [dose-response relationship] was observed.

Finding Relief in the Desert: Managing Paget's Disease with Tiludronate

This research offers hope for individuals [living with Paget's disease]. [Tiludronate] may be a [valuable treatment option] that can [alleviate symptoms] and [improve quality of life]. It's like [discovering a hidden spring] in the [desert landscape] of [Paget's disease], offering [relief and rejuvenation] to those affected.

Dr.Camel's Conclusion

This study highlights the [potential of tiludronate] as a [treatment option] for [Paget's disease] and encourages [further research] to explore its [long-term effects] and [potential for improvement].

Date :
  1. Date Completed 1997-10-21
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

9307742

DOI: Digital Object Identifier

10.1136/pgmj.73.862.496

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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