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Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.

Author: McLaughlinJ, MorrisJ, StellyM, VolicerB J, VolicerL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

Dronabinol may be beneficial for treating anorexia and improving disturbed behavior in patients with Alzheimer's disease. It showed promise in improving body weight and behavior with manageable side effects.
Paper Details　
Original Abstract of the Article :
A placebo-controlled crossover design, with each treatment period lasting 6 weeks, was used to investigate effects of dronabinol in 15 patients with a diagnosis of probable Alzhemer's disease who were refusing food. Eleven patients completed both study periods; one patient who died of a heart attack...See full text at original site
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引用元：
https://doi.org/10.1002/(SICI)1099-1166(199709)12:9<913::AID-GPS663>3.0.CO;2-D

データ提供：米国国立医学図書館（NLM）

Dronabinol: A Promising Treatment for Alzheimer's Disease

This study delves into the use of dronabinol, a synthetic form of THC, for treating anorexia and behavioral disturbances in patients with Alzheimer's disease. Imagine this as a quest to find a solution for the complex challenges posed by this debilitating disease.

The researchers conducted a placebo-controlled crossover study to investigate the effects of dronabinol in patients with Alzheimer's disease who were refusing food. They carefully measured changes in body weight, behavior, and side effects during different treatment periods. This is like observing the effects of a particular herb in the desert, noting its potential benefits and risks.

The study found that dronabinol treatment led to increased body weight and a decrease in behavioral disturbances in patients with Alzheimer's disease. While there were some side effects, these were generally manageable. This is like discovering a new herb that can alleviate hunger and restlessness in the desert, offering a potential solution for those who are struggling.

A New Path for Treating Alzheimer's

The study suggests that dronabinol may be a promising treatment option for managing anorexia and behavioral disturbances in patients with Alzheimer's disease.

Navigating the Desert of Alzheimer's Disease

This research provides valuable insights into potential treatment options for Alzheimer's disease, a challenging condition that affects millions worldwide. By exploring new therapies and understanding their potential benefits and risks, we can offer hope and support for those living with this complex disease. It's like finding a new oasis in the vast desert of Alzheimer's, offering a glimmer of hope for a better future.

Dr.Camel's Conclusion

This study underscores the importance of exploring new therapeutic approaches for Alzheimer's disease. Dronabinol's potential to address both anorexia and behavioral disturbances offers a glimmer of hope in the ongoing quest for treatments that can improve the lives of those living with this debilitating disease.

Date :
  1. Date Completed 1997-11-25
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

9309469

DOI: Digital Object Identifier

10.1002/(SICI)1099-1166(199709)12:9<913::AID-GPS663>3.0.CO;2-D

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・Effects of dronabinol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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