Management of NSAID-induced gastropathy: an economic decision analysis.

Author: BoydM S, GoldsteinJ L, LarsonL R, YamashitaB D

Paper Details 
Original Abstract of the Article :
The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a 2% to 4% annual incidence of serious gastrointestinal complications. These adverse clinical outcomes, and the strategies used to prevent their occurrence, translate into a significant economic burden. A decision-analysis m...See full text at original site
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引用元:
https://doi.org/10.1016/s0149-2918(97)80021-5

データ提供:米国国立医学図書館(NLM)

NSAIDs and Gastropathy: A Balancing Act

The world of medicine is like a vast desert, with challenges and opportunities stretching out in every direction. One such challenge is managing the side effects of nonsteroidal anti-inflammatory drugs (NSAIDs), which are like a double-edged sword. They can effectively relieve pain, but they also carry the risk of gastropathy, which is like a sandstorm in your stomach! This research delves into the intricate dance between NSAIDs and the stomach, analyzing the economic impact of different strategies for managing this gastrointestinal dilemma. The study used a decision-analysis model to compare the 6-month costs of various approaches, including using NSAIDs alone, combining them with histamine2-receptor antagonists, or prescribing misoprostol alongside. The researchers found that fixed-dose combinations of diclofenac/misoprostol demonstrated a significant cost advantage compared to other treatment regimens.

Cost-Effective Solutions: A Guiding Star in the Desert

This study suggests that utilizing fixed-dose diclofenac/misoprostol regimens can lead to a substantial cost reduction for patients, potentially saving up to $214 per patient over a 6-month period. This information can be a valuable tool for clinicians, like a compass guiding them towards a more cost-effective and rational approach to managing patients requiring chronic NSAID therapy.

Navigating the Sands of Gastropathy

The research findings can help guide clinicians in selecting treatment options that are both safe and economically feasible. It emphasizes the importance of considering the long-term consequences of NSAID use and the need for tailored strategies to minimize the risk of gastropathy. It's like navigating a desert, where careful planning and resource management are crucial for a successful journey.

Dr.Camel's Conclusion

This research sheds light on the intricate interplay between NSAIDs, gastropathy, and cost-effectiveness. It provides a valuable framework for clinicians to navigate the challenging terrain of managing NSAID-induced gastropathy in a way that balances clinical efficacy with economic considerations. It’s like finding an oasis in a vast desert, offering a solution to a pressing medical concern.

Date :
  1. Date Completed 1998-03-05
  2. Date Revised 2019-09-21
Further Info :

Pubmed ID

9444455

DOI: Digital Object Identifier

10.1016/s0149-2918(97)80021-5

Related Literature

SNS
PICO Info
in preparation
Languages

English

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