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Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids.

Author: BootsmaG P, DekhuijzenP N, FestenJ, WieldersP L, van HerwaardenC L, van den BergL R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Zileuton, a 5-lipoxygenase inhibitor, attenuated bronchial hyperresponsiveness to histamine and ultrasonically nebulized distilled water in asthmatic patients with marked bronchial hyperresponsiveness.
Paper Details　
Original Abstract of the Article :
The aim of the study was to determine whether zileuton, an inhibitor of 5-lipoxygenase, attenuated bronchial hyperresponsiveness (BHR) in asthmatic subjects who had marked BHR during maintenance treatment with inhaled corticosteroids (ICS). In a randomized, double-blind, placebo-controlled, cross-ov...See full text at original site
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引用元：
https://doi.org/10.1183/09031936.97.10122749

データ提供：米国国立医学図書館（NLM）

Zileuton and Bronchial Hyperresponsiveness: A Breath of Fresh Air

Pulmonary research, like a vast and intricate landscape, is constantly exploring new ways to manage respiratory conditions. This study examines the effects of single-dose zileuton, an inhibitor of 5-lipoxygenase, on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids. The researchers used a [research methodology] to investigate the impact of zileuton on bronchial hyperresponsiveness in asthmatic patients. They discovered that [key findings]. This study offers valuable insights into the potential therapeutic benefits of zileuton for managing asthma symptoms.

Zileuton: An Oasis in the Desert of Asthma

This study suggests that zileuton can effectively attenuate bronchial hyperresponsiveness in asthmatic patients. This finding offers a potential new avenue for managing asthma symptoms, providing patients with a breath of fresh air and improved quality of life.

Navigating the Desert of Asthma: Managing Symptoms

If you have asthma, follow your doctor's recommendations for managing your condition. Take your medications as prescribed, avoid triggers that worsen your symptoms, and practice good respiratory hygiene. Stay informed about your condition and participate actively in your treatment plan.

Dr. Camel's Conclusion

This study highlights the potential of zileuton as a valuable tool for managing bronchial hyperresponsiveness in asthmatic patients. The research, like a refreshing oasis in the desert of asthma symptoms, provides a promising new avenue for treatment and improved quality of life for patients.

Date :
  1. Date Completed 1998-04-23
  2. Date Revised 2019-08-22
Further Info :

Pubmed ID

9493655

DOI: Digital Object Identifier

10.1183/09031936.97.10122749

Related Literature

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・Effects of zileuton
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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