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Clinical pharmacokinetics of the antiandrogens and their efficacy in prostate cancer.

Author: DenisL, MahlerC, VerhelstJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Antiandrogens, such as bicalutamide, are used to treat prostate cancer, particularly in metastatic cases. Bicalutamide has a longer half-life than flutamide, allowing once-daily administration, and is associated with fewer adverse effects compared to nilutamide.
Paper Details　
Original Abstract of the Article :
Prostatic cancer is the second most common cause of cancer death in males. Treatment by radical prostatectomy and radiotherapy is useful in the early stages of the disease. Whenever metastases occur, patients are usually treated by surgical (orchidectomy) or medical [gonadotropin releasing hormone (...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.2165/00003088-199834050-00005

データ提供：米国国立医学図書館（NLM）

Prostate Cancer: A Desert of Hormonal Warfare

Prostate cancer is a challenging foe, a formidable desert to conquer. This study explores the use of antiandrogens in the treatment of prostate cancer, a battleground where hormones play a crucial role. The researchers discuss the different types of antiandrogens and their effectiveness in blocking androgen activity, the key to controlling the growth of this aggressive cancer. This study is like a detailed battle plan, outlining the different strategies for fighting prostate cancer with antiandrogens.

Antiandrogens: Weapons in the Hormonal War

This study sheds light on the use of antiandrogens in prostate cancer treatment. These drugs, like potent weapons, block androgen activity, hindering the growth and spread of this aggressive cancer.

Navigating the Complexities of Prostate Cancer Treatment

The realm of prostate cancer treatment is a complex and often challenging desert. This study offers valuable insights into the use of antiandrogens, a potential oasis of relief for patients battling this disease. Further research is needed to refine our understanding of these treatments and explore their potential for combination therapies, but this study offers a valuable contribution to our arsenal of weapons against this formidable foe.

Dr.Camel's Conclusion

This study provides a valuable overview of antiandrogen therapy in prostate cancer. These drugs, like powerful weapons, block androgen activity, a key factor in the growth and spread of this disease. By understanding the different types of antiandrogens and their potential benefits and risks, we can better navigate the challenging desert of prostate cancer treatment and develop more effective strategies for battling this formidable foe.

Date :
  1. Date Completed 1998-07-23
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

9592622

DOI: Digital Object Identifier

10.2165/00003088-199834050-00005

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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