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A single-blind, crossover comparison of the pharmacokinetics and cognitive effects of a new diazepam rectal gel with intravenous diazepam.
Author: BeniakT E, CloydJ C, LalondeR L, NovackG D
Original Abstract of the Article :
PURPOSE: The objective of this study was to compare the pharmacokinetics and cognitive effects of a new diazepam (DZP) rectal gel (Diastat) with intravenously administered DZP. METHODS: Twenty healthy volunteers were enrolled in a single-blind, randomized, double-dummy, two-period, crossover study....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1528-1157.1998.tb01415.x
データ提供:米国国立医学図書館(NLM)
Diazepam Rectal Gel: A New and Effective Route for Anxiety Relief
This research compares the effectiveness of a new diazepam rectal gel with intravenous diazepam for treating anxiety. Imagine anxiety as a scorching desert sun, causing you to feel overwhelmed and uneasy. Diazepam is a medication that can provide relief from anxiety, but traditional methods of administration, such as intravenous injection, can be inconvenient. This study explores a new rectal gel formulation of diazepam, offering a potentially easier and more comfortable way to administer the medication. The researchers conducted a single-blind, crossover study, comparing the pharmacokinetics (how the body absorbs and processes the drug) and cognitive effects of the rectal gel with intravenous diazepam. The findings suggest that the rectal gel provides rapid and consistent absorption of diazepam, similar to intravenous administration, while producing minimal cognitive side effects. This study offers promising evidence for the use of rectal diazepam gel as a safe and effective alternative to intravenous administration, potentially improving patient comfort and convenience.
Diazepam Rectal Gel: A New Frontier in Anxiety Treatment
This research highlights the potential of diazepam rectal gel as a safe and effective alternative to intravenous administration for treating anxiety. The findings offer a new and potentially more comfortable way to administer diazepam, potentially improving patient experience and convenience.
Navigating Anxiety: Finding the Right Treatment
Anxiety is a common condition that can have a significant impact on quality of life. This study encourages exploring different treatment options, including new and innovative approaches, to find the best fit for individual needs and preferences.
Dr.Camel's Conclusion
This study, like a cool desert breeze, offers a refreshing approach to anxiety treatment. The researchers are exploring new and innovative ways to administer diazepam, potentially enhancing patient comfort and convenience. This research is a testament to the ongoing quest for more effective and patient-centered treatment approaches.
Date :
- Date Completed 1998-06-02
- Date Revised 2019-08-13
Further Info :
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