[Cephalosporins in the treatment of children with oncohematologic diseases].

Author: ErinaT A, KondratchikK L, MakhortykhT Zh, Nepokul'chitskaiaN V, TarasovaI S, TimakovA M

Paper Details 
Original Abstract of the Article :
Clinical efficacy of 3rd generation cephalosporins i.e. oral cefpodoxime and parenteral ceftriaxone was studied in the treatment of children with oncohematologic pathology. Cefpodoxime proved to be efficient in cases of moderate infectious complications in regard to the respiratory tracts. The oral ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/9606502

データ提供:米国国立医学図書館(NLM)

Cephalosporins: A Powerful Weapon Against Infections in Pediatric Oncology

Children with oncohematologic diseases, such as leukemia and lymphoma, often face a weakened immune system, making them susceptible to infections. This study investigates the efficacy of third-generation cephalosporins, cefpodoxime and ceftriaxone, in treating children with oncohematologic pathology. The researchers evaluated the effectiveness of these antibiotics in managing both moderate and severe infectious complications in this vulnerable patient population.

Cephalosporins: A Vital Tool for Pediatric Oncology

The study found that both cefpodoxime and ceftriaxone demonstrated promising efficacy in treating infections in children with oncohematologic diseases. Cefpodoxime, given orally, proved effective in managing moderate respiratory tract infections, allowing for outpatient treatment. Ceftriaxone, administered intravenously, effectively addressed more severe infections often associated with agranulocytosis and weakened immune responses. These findings highlight the critical role of cephalosporins in combating infections and improving outcomes for children undergoing cancer treatment.

Protecting Vulnerable Patients: A Multifaceted Approach

This study underscores the importance of effective antibiotic therapy in managing infections in children with oncohematologic diseases. By providing targeted treatment with appropriate antibiotics, healthcare professionals can minimize the risks of infection, reduce morbidity, and improve the overall health and well-being of these vulnerable patients. This research emphasizes the need for a multifaceted approach to caring for children with cancer, incorporating not only cancer treatment but also proactive infection prevention and management strategies.

Dr.Camel's Conclusion

Imagine a vast desert oasis, a refuge for weary travelers. For children battling cancer, the journey can be grueling and fraught with challenges. This study highlights the importance of cephalosporins, antibiotics that serve as a vital resource in protecting these vulnerable patients from the threat of infections. Just as a camel relies on its resilience to navigate the harsh desert, these children need the support of advanced medical treatments and vigilant care to overcome the obstacles of their illness.

Date :
  1. Date Completed 1998-08-13
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

9606502

DOI: Digital Object Identifier

9606502

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PICO Info
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Languages

Russian

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