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Goserelin acetate (Zoladex) with or without hormone replacement therapy for the treatment of endometriosis.

Author: MoghissiK S, OliveD L, SchlaffW D, SkinnerM A, YinH

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study aimed to determine if adding hormone replacement therapy (HRT) to goserelin treatment for endometriosis would be as effective in reducing pelvic pain as goserelin alone, and whether it would also prevent bone loss and other side effects associated with goserelin.
Paper Details　
Original Abstract of the Article :
To determine whether hormone replacement therapy (HRT) plus goserelin (Zoladex) is as effective as goserelin alone for the relief of pelvic symptoms of endometriosis and to determine whether it reduces both the loss of bone mineral density (BMD) and the physiologic side effects associated with goser...See full text at original site
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引用元：
https://doi.org/10.1016/s0015-0282(98)00086-7

データ提供：米国国立医学図書館（NLM）

Goserelin Acetate: A Beacon of Hope in the Desert of Endometriosis

The [endometriosis] landscape, often a challenging desert with persistent pain and discomfort, has seen advancements in treatment. This study explores the effectiveness of [goserelin acetate (Zoladex)], a medication commonly used to treat endometriosis, with and without [hormone replacement therapy (HRT)]. The researchers conducted a comparative study, analyzing the impact of these treatments on [pelvic symptoms, bone mineral density (BMD), and physiological side effects]. Their findings provide valuable insights into the potential benefits and risks of using goserelin acetate, both alone and in combination with HRT, for managing endometriosis.

Navigating the Desert of Endometriosis: Finding Relief and Preserving Bone Health

This research, like a camel caravan venturing through a desert of pain, offers potential solutions for those battling endometriosis. The study's findings suggest that goserelin acetate, both alone and in combination with HRT, can effectively reduce pelvic symptoms associated with endometriosis. However, the study also highlights the potential for bone loss, emphasizing the importance of careful monitoring and individualized treatment plans to optimize outcomes while minimizing side effects.

Endometriosis: A Long Journey with Personalized Care

The journey through endometriosis can be long and challenging. This study underscores the importance of personalized treatment plans that address both symptom relief and the preservation of bone health. By carefully considering the potential benefits and risks of different treatment options, healthcare professionals can help patients navigate this complex landscape, creating a path towards a better quality of life.

Dr. Camel's Conclusion

This research, like a camel caravan discovering a new oasis in the desert of endometriosis, offers potential solutions for managing this condition. The study's findings suggest that goserelin acetate, both alone and in combination with HRT, can effectively reduce pelvic symptoms, but it's important to be aware of the potential for bone loss. Remember, friends, navigating the desert of chronic illness requires a personalized approach, informed decision-making, and a relentless pursuit of well-being.

Date :
  1. Date Completed 1998-07-07
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

9627292

DOI: Digital Object Identifier

10.1016/s0015-0282(98)00086-7

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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