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Effects of subchronic administration of clozapine, thioridazine and haloperidol on tests related to extrapyramidal motor function in the rat.
Author: AbermanJ, AthertonA, SalamoneJ D, TrevittJ
Original Abstract of the Article :
Clozapine, thioridazine (THIO) and haloperidol were administered for 14 consecutive days, and separate groups of rats were used to study the effects of these drugs on tremulous jaw movements and lever pressing. Rats were observed on day 13 for the ability of the antipsychotic drugs to induce jaw mov...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s002130050593
データ提供:米国国立医学図書館(NLM)
Atypical Antipsychotics: A Camel's Journey Through the Desert of Extrapyramidal Side Effects
Antipsychotic medications, like a camel's trusty pack, are essential for treating mental health conditions. However, some antipsychotics can cause unpleasant side effects, like extrapyramidal symptoms, which can feel like navigating a desert filled with thorny bushes. This research, like a camel seeking a smoother path through the desert, investigates the effects of different antipsychotic drugs on extrapyramidal motor function in rats.
The study, using a rat model, found that clozapine, an atypical antipsychotic, was less likely to induce extrapyramidal symptoms compared to haloperidol, a typical antipsychotic. This finding is like discovering a hidden oasis in the desert - a place where the journey is smoother and less arduous. The study also examined the effects of these drugs on other behaviors, like lever pressing, providing further insights into their potential benefits and risks.
Atypical Antipsychotics: A Camel's Search for a Smoother Path
This research highlights the potential benefits of atypical antipsychotics, like clozapine, in reducing extrapyramidal side effects. This finding is like discovering a smoother path through the desert, one that reduces the risk of encountering thorny obstacles.
Mental Health Treatment: A Camel's Guide to Finding the Right Path
Mental health conditions can be challenging to treat, like navigating a vast and unfamiliar desert. This research provides valuable information for clinicians seeking to find the most effective and safe treatments for their patients. It's a reminder that understanding the potential benefits and risks of different medications is crucial for finding the right path to mental wellness.
Dr.Camel's Conclusion
This research offers hope for patients struggling with extrapyramidal side effects from antipsychotic medications. Atypical antipsychotics, like clozapine, may offer a smoother and less burdensome journey through the desert of mental health treatment. It's a reminder that continued research and exploration are crucial for finding the best solutions for those who need them.
Date :
- Date Completed 1998-08-06
- Date Revised 2019-07-26
Further Info :
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