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Acute effects of the oral administration of midodrine, an alpha-adrenergic agonist, on renal hemodynamics and renal function in cirrhotic patients with ascites.
Author: AngeliP, BortoluzziA, BottaroS, CasigliaE, CraigheroR, De ToniR, FinucciG F, GattaA, PavanL, PiovanD, SticcaA, VolpinR
Original Abstract of the Article :
The effects of the acute administration of arterial vasoconstrictors on renal plasma flow (RPF) and urinary sodium excretion (UNaV) in cirrhotic patients with ascites with or without hepatorenal syndrome (HRS) are still controversial. As a consequence, vasoconstrictors are not actually used in the t...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/hep.510280407
データ提供:米国国立医学図書館(NLM)
Midodrine: A Potential Oasis in the Desert of Liver Disease
Dr. Camel here, your guide through the often challenging landscape of liver disease, a condition that can feel like navigating a desert where resources are scarce.This study examines the acute effects of midodrine, an alpha-adrenergic agonist, on renal hemodynamics and function in patients with cirrhosis and ascites. Think of this as exploring a new oasis in the desert of liver disease, testing the waters to see if they can offer relief.
A New Source of Hydration in the Desert of Cirrhosis
The study found that midodrine, an oral medication, significantly improved systemic hemodynamics in non-azotemic patients with cirrhosis and ascites. This improvement was associated with better renal perfusion and sodium excretion. The results are like discovering a new spring in the desert, offering a potential lifeline for those struggling with fluid retention.Health Implications and Practical Applications
This research may have important implications for the treatment of patients with cirrhosis and ascites. It's essential to discuss these new findings with your doctor to determine if midodrine might be an appropriate treatment option for you.Dr. Camel's Conclusion
This study offers a glimmer of hope in the midst of the challenges posed by liver disease. It's a reminder that even in the most barren deserts of illness, there are often new oases waiting to be discovered.Date :
- Date Completed 1998-11-05
- Date Revised 2013-11-21
Further Info :
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