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Effect of RenaGel, a non-absorbed, calcium- and aluminium-free phosphate binder, on serum phosphorus, calcium, and intact parathyroid hormone in end-stage renal disease patients.

Author: BurkeS K, DillonM A, GarrettB, GoldbergD I, GrayJ R, MarburyT, SlatopolskyE A, WeinbergM, WomboltD

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examined the efficacy of RenaGel, a calcium- and aluminium-free polymeric phosphate binder, in end-stage renal disease patients as a potential alternative to calcium- and aluminium-containing binders, which have associated side effects.
Paper Details　
Original Abstract of the Article :
Control of dietary phosphate absorption in end-stage renal disease patients is essential to prevent the deleterious sequelae of phosphorus retention. Efficacy of currently available calcium- and aluminium-containing phosphate binders is constrained by the side-effects associated with the absorption ...See full text at original site
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引用元：
https://doi.org/10.1093/ndt/13.9.2303

データ提供：米国国立医学図書館（NLM）

RenaGel: A New Phosphate Binder for End-Stage Renal Disease

Managing phosphate levels in patients with end-stage renal disease is crucial for preventing complications. However, existing phosphate binders, which often contain calcium and aluminum, can have significant side effects. This study explores the efficacy of RenaGel, a calcium- and aluminum-free phosphate binder, in patients with end-stage renal disease.

The study found that RenaGel effectively controlled serum phosphorus levels without the side effects associated with traditional phosphate binders. The researchers observed a significant reduction in serum phosphorus levels in patients treated with RenaGel.

RenaGel: A Safer and More Effective Approach

This study provides strong evidence for the efficacy and safety of RenaGel as a phosphate binder for patients with end-stage renal disease. RenaGel offers a promising alternative to traditional binders, potentially improving patient outcomes and reducing the risk of complications associated with calcium and aluminum absorption.

Dr. Camel's Conclusion

This research offers a beacon of hope for patients with end-stage renal disease. RenaGel offers a safe and effective alternative to traditional phosphate binders, potentially improving patient outcomes and reducing the risk of complications. It's a testament to the ongoing quest for better treatment options in the ever-evolving field of medicine.

Date :
  1. Date Completed 1998-12-23
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

9761513

DOI: Digital Object Identifier

10.1093/ndt/13.9.2303

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