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Chinese herbs nephropathy-associated slimming regimen induces tumours in the forestomach but no interstitial nephropathy in rats.
Author: BernardA M, BielerC A, CosynsJ P, GoebbelsR M, LibertonV, SchmeiserH H
Original Abstract of the Article :
Chinese herbs nephropathy (CHN), a rapidly progressive interstitial fibrosis of the kidney, has been described in approximately 100 young Belgian women who had followed a slimming regimen containing some Chinese herbs. In 4 patients multifocal transitional cell carcinomas (TCC) were observed. Aristo...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s002040050568
データ提供:米国国立医学図書館(NLM)
Investigating the Link between Chinese Herbs Nephropathy and Cancer
The world of herbal medicine is a vast and intricate landscape, with numerous remedies holding both potential benefits and hidden risks. This research explores the association between Chinese herbs nephropathy (CHN), a severe kidney disorder, and the development of cancer. The study investigates the potential role of aristolochic acid (AA), a component of some Chinese herbs, in both CHN and carcinogenesis. The authors conducted experiments using rats to determine whether AA could induce both fibrosis and tumor formation. Their findings revealed that AA effectively induced tumor development in rats, but did not lead to fibrosis of the renal interstitium. These results suggest that the fibrotic response observed in humans may be due to species-specific differences or other contributing factors.
The Complex Relationship between CHN and Cancer
This study provides valuable insights into the potential link between CHN and cancer, highlighting the need for further investigation into the role of AA in these conditions. The findings suggest that the mechanisms underlying CHN may be different in humans and animals, necessitating a more nuanced understanding of the factors involved.
Navigating the Risks of Herbal Remedies
The study underscores the importance of exercising caution when using herbal remedies, as some ingredients may pose significant health risks. This research highlights the need for rigorous scientific investigation to assess the safety and efficacy of herbal medications, particularly those with known carcinogenic potential.
Dr. Camel's Conclusion
Just as a camel must carefully navigate treacherous desert terrain, understanding the potential risks and benefits of herbal remedies is paramount. This research sheds light on the complex interplay between herbal medicine, CHN, and cancer, reminding us to approach these substances with caution and seek guidance from qualified healthcare professionals.
Date :
- Date Completed 1999-04-29
- Date Revised 2019-09-05
Further Info :
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