Polygraphic sleep studies in rats and humans: their use in psychopharmacological research.

Author: LoewD M, SpiegelR

Paper Details 
Original Abstract of the Article :
The effects of selected centrally acting drugs on sleep after single administration to rats and humans were studied using polygraphic sleep recording techniques. D-Amphetamine, a stimulant, had similar effects in both species: reduction of total sleep time, of N(non-)REM- and particularly REM (rapid...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/989373

データ提供:米国国立医学図書館(NLM)

The Power of Polygraphic Sleep Studies: Unveiling the Secrets of the Brain

This study explores the use of [polygraphic sleep studies] in [psychopharmacological research], comparing the effects of various drugs on sleep patterns in both rats and humans. The study demonstrates the sensitivity and specificity of polygraphic sleep studies in identifying the effects of different drug classes on sleep architecture. The findings highlight the value of this technique in understanding the mechanisms of action of drugs and their impact on the brain.

Across Species and Drug Classes: Sleep Studies Offer a Window into the Brain

The study, like a skilled caravan guide navigating a diverse landscape, demonstrates the versatility of polygraphic sleep studies in examining the effects of drugs across species and drug classes. The findings suggest that this technique can provide valuable insights into the [neuropharmacological effects] of drugs, offering a window into the complex workings of the brain. This research underscores the importance of [animal models] in understanding the effects of drugs and their potential applications in human medicine.

A Powerful Tool for Research: Illuminating the Mechanisms of Sleep and Wakefulness

The study's findings underscore the value of [polygraphic sleep studies] as a tool for [drug discovery and development]. By understanding the effects of drugs on sleep patterns, researchers can gain valuable insights into the [neurobiological mechanisms] underlying sleep and wakefulness. This knowledge can lead to the development of [more targeted and effective drugs] for treating sleep disorders and other neurological conditions.

Dr.Camel's Conclusion

This study, like a wise old camel sharing its knowledge of the desert's secrets, reminds us that sleep is a complex and fascinating process. Polygraphic sleep studies, like a powerful telescope exploring the vast universe of the brain, provide valuable insights into the workings of our minds and the impact of drugs on our sleep patterns. This research is a testament to the power of science to unravel the mysteries of the human mind and create a better future for all.

Date :
  1. Date Completed 1976-11-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

989373

DOI: Digital Object Identifier

989373

Related Literature

SNS
PICO Info
in preparation
Languages

English

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