Effective treatment of diabetic kidney problems: A Synthesis of Findings from 15 Studies

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Original Abstract of the Article

Major Research Findings

Several studies have investigated different treatments for dizziness. For example, 1 found that 1% ephedrine hydrochloride nasal douche provided relief for 74.3% of vertigo patients. 4 indicated that vestibular rehabilitation, a specialized treatment for dizziness, was beneficial for patients, leading to improvements in symptoms, disability, handicap, and postural stability. Another study, 11 , found that combining vestibular rehabilitation with transcranial direct current stimulation (tDCS) showed promise for treating chronic vestibular dysfunction in older adults. Additional research suggests that head-up sleep (HUS) and vertical recognition training (VRT) may be effective for treating intractable motion-evoked dizziness, including possible benign paroxysmal positional vertigo (BPPV). 10 Moreover, 13 suggests that canalith repositioning maneuvers (CRMs) might be superior to vestibular suppressants for treating BPPV.

Treatment Summary

1 highlighted 1% ephedrine hydrochloride nasal douche as a potential treatment option. Meanwhile, 4 and 11 advocate for vestibular rehabilitation. 10 explored the effectiveness of combining head-up sleep (HUS) and vertical recognition training (VRT) for BPPV, while 13 suggests that canalith repositioning maneuvers (CRMs) might be a preferable option over medications for treating BPPV.

Benefits and Risks

Benefit Summary

The research indicates that various treatments hold the potential to alleviate dizziness symptoms. Notably, vestibular rehabilitation has shown effectiveness in improving symptoms, disability, handicap, and postural stability. 4 Additionally, 11 suggests that combining vestibular rehabilitation with transcranial direct current stimulation (tDCS) may be beneficial for treating chronic vestibular dysfunction in older adults.

Risk Summary

Many studies report minimal side effects. 1 However, certain treatments might carry potential risks. For instance, ephedrine hydrochloride nasal douche could lead to nasal inflammation or nosebleeds. 1 Transcranial direct current stimulation (tDCS) may cause side effects like headaches or nausea. 11 It is crucial to consult with a doctor before starting any treatment to ensure it is appropriate for your condition.

Comparison of Studies

Commonalities of Studies

A significant number of studies suggest that vestibular rehabilitation is effective in improving dizziness symptoms. Most research reports minimal side effects.

Differences in Studies

Each study focuses on different types of dizziness and treatment approaches. 1 focuses on ephedrine hydrochloride nasal douche while 4 and 11 emphasize vestibular rehabilitation. 10 explores the combination of head-up sleep (HUS) and vertical recognition training (VRT) for BPPV, and 13 highlights the potential benefits of canalith repositioning maneuvers (CRMs) over medications for treating BPPV.

Consistency and Inconsistencies of Results

Numerous studies indicate the effectiveness of vestibular rehabilitation in alleviating dizziness symptoms. However, given the variations in study designs, types of dizziness, and treatment methods, drawing definitive conclusions about the most effective treatment remains challenging. Further research is necessary.

Implications for Everyday Life

If you are experiencing dizziness, it is highly recommended to consult a doctor. They can diagnose the underlying cause of your dizziness and recommend appropriate treatment. Treatment options will vary depending on the cause and severity of your dizziness. It is crucial to undergo any prescribed treatment, such as vestibular rehabilitation, under the guidance of a healthcare professional.

Limitations of Current Research

Many studies are limited by small sample sizes and a narrow focus on specific types of dizziness and treatments. Larger-scale studies are needed to provide more comprehensive evidence. Research regarding long-term effects and safety also requires further investigation.

Future Research Directions

To develop more effective treatments for various types of dizziness, larger-scale research is essential. Long-term effects and safety studies are particularly crucial. Research tailored to individual patient characteristics and symptoms is needed to develop personalized treatment strategies.

Conclusion

Dizziness can have many different causes. While numerous studies suggest that vestibular rehabilitation is effective in improving dizziness symptoms, there is no definitive answer regarding the most effective treatment. Further research is essential to understand the most effective treatments for various types of dizziness and to determine the long-term effects and safety of different approaches. If you are experiencing dizziness, consulting a doctor is the first step to getting the proper diagnosis and treatment.

List of Treatments

  • 1% ephedrine hydrochloride nasal douche
  • Vestibular rehabilitation
  • Transcranial direct current stimulation (tDCS)
  • Head-up sleep (HUS)
  • Vertical recognition training (VRT)
  • Canalith repositioning maneuvers (CRMs)
Literature analysis of 15 papers
Positive Content
14
Neutral Content
1
Negative Content
0
Article Type
11
1
4
4
15
1.

A simple, effective method of treating vertigo patients.

Author: BaserB, KackerS K

Vertigo treatment

This study investigated the effectiveness of a nasal spray containing ephedrine hydrochloride in treating dizziness (vertigo) in 84 patients. The treatment resulted in complete or partial relief of dizziness in 74.3% of patients. The treatment was well-tolerated and had minimal side effects. This suggests that ephedrine hydrochloride nasal spray may be a promising treatment for vertigo.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

2.

Dizziness in children.

Author: EviatarL

dizziness treatment
dizziness

This paper discusses the diagnosis and treatment of dizziness in children, emphasizing the need for a thorough evaluation and algorithmic approach to reach an accurate diagnosis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

3.

A randomized controlled trial of exercise therapy for dizziness and vertigo in primary care.

Author: YardleyL, BeechS, ZanderL, EvansT, WeinmanJ

Improved balance
Reduced distress
Reduced dizziness

This randomized controlled trial found that vestibular rehabilitation (VR) is a simple, inexpensive, and beneficial treatment for patients with dizziness in primary care. The study suggests that VR may be an appropriate first stage of management for many dizzy patients.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

4.

Feasibility and effectiveness of providing vestibular rehabilitation for dizzy patients in the community.

Author: YardleyL, BurgneayJ, AnderssonG, OwenN, NazarethI, LuxonL

Improved dizziness
Vestibular rehabilitation

This study examined the need and feasibility of providing vestibular rehabilitation for patients with dizziness in the community. The study found that while there was a significant demand for therapy, only a small percentage of patients were suitable and willing to attend hospital for testing and rehabilitation.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Effectiveness of primary care-based vestibular rehabilitation for chronic dizziness.

Author: YardleyLucy, Donovan-HallMargaret, SmithHelen E, WalshBronagh M, MulleeMark, BronsteinAdolfo M

Improved dizziness symptoms

Nurse-delivered vestibular rehabilitation improves symptoms, postural stability, and dizziness-related handicap in patients with chronic dizziness.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Cervicogenic dizziness - musculoskeletal findings before and after treatment and long-term outcome.

Author: MalmströmEva-Maj, KarlbergMikael, MelanderAgneta, MagnussonMåns, MoritzUlrich

Dizziness reduction
Neck pain relief

Patients with suspected cervicogenic dizziness have some musculoskeletal findings in common. Treatment based on these findings reduces neck pain as well as dizziness long-term but some patients might need a maintenance strategy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

[Analyses of clinical features and efficacy of sudden deafness with vertigo and dizziness].

Author: LiuBo, HanDemin, ZhangYi, LiYongxin, GongShusheng, ChenXiuwu, MengXixi, TangJunxiang, XiangJie, JiangXuejun, YangNing, TianYing, HuiLian, FengShuai,

Improved hearing
Reduced vertigo
Lower chance of full hearing recovery

The study found that the standard treatment for sudden hearing loss with vertigo or dizziness was effective in reducing symptoms and improving hearing. The best results were seen in patients with low and intermediate frequency descent type hearing loss, followed by flat type hearing loss.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : Chinese

8.

Evalution of the effectiveness of multimodal approach to the management of cervical vertigo.

Author: JaroshevskyiOlexandr A, PayenokOleksandr S, LogvinenkoAnna V

Cervical vertigo treatment

Vertigo (a feeling of dizziness) is a common complaint that doctors often see. Cervical vertigo is a specific type of dizziness caused by problems in the neck. For people with chronic dizziness and balance problems, vestibular rehabilitation therapy is a potential treatment option.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

9.

Implementation of Evidence-Based Practice for Benign Paroxysmal Positional Vertigo in the Emergency Department: A Stepped-Wedge Randomized Trial.

Author: KerberKevin A, DamschroderLaura, McLaughlinThomas, BrownDevin L, BurkeJames F, TelianSteven A, TsodikovAlexander, FagerlinAngela, AnLawrence C, MorgensternLewis B, FormanJane, VijanSandeep, RowellBrigid, MeurerWilliam J

Reduced head CT use

This stepped-wedge randomized trial found that an implementation strategy of a benign paroxysmal positional vertigo-focused approach to ED dizziness visits can be successful and safe in promoting evidence-based care. Absolute rates of DHT and CRM use were still low, however, which relates in part to the broad inclusion criteria for dizziness visits.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

10.

Combination of head-up sleep and vertical recognition training may cure intractable motion-evoked dizziness with unknown origin.

Author: KitaharaTadashi, HorinakaAkira, ShiozakiTomoyuki, ItoTaeko, WadaYoshiro, YamanakaToshiaki, NarioKazuhiko

Reduced dizziness

This study assessed the effectiveness of head-up sleep (HUS) and vertical recognition training (VRT) for intractable motion-evoked dizziness, including possible benign paroxysmal positional vertigo (BPPV). The HUS+/VRT+ group had the lowest visual analogue scale (VAS) scores for vertiginous sensation at 6 months. These results suggest that both HUS and VRT are effective treatments for intractable motion-evoked dizziness.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

11.

Vestibular rehabilitation therapy in combination with transcranial direct current stimulation (tDCS) for treatment of chronic vestibular dysfunction in the elderly: a double-blind randomized controlled trial.

Author: SakiNader, BayatArash, NikakhlaghSoheila, MirmomeniGolshan

Improved balance function

This study investigated the potential benefits of transcranial direct current stimulation (tDCS) in combination with vestibular rehabilitation therapy for dizziness and imbalance in elderly patients with vestibular dysfunction.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

12.

Home-based Vestibular Rehabilitation: A Feasible and Effective Therapy for Persistent Postural Perceptual Dizziness (A Pilot Study).

Author: TehCarren Sui-Lin, AbdullahNurul Ain, KamaruddinNoor Rafidah, Mohd JudiKamariah Binti, FadzilahIsmail, ZainunZuraida, PrepageranNarayanan

Treatment for PPPD

This study discusses treatment recommendations for persistent postural-perceptual dizziness (PPPD), a chronic functional vestibular disorder characterized by persistent dizziness or unsteadiness. Treatment approaches typically involve vestibular rehabilitation therapy (VRT), medications, and/or cognitive behavioral therapy.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

13.

Vestibular suppressants for benign paroxysmal positional vertigo: A systematic review and meta-analysis of randomized controlled trials.

Author: SharifSameer, KhoujahDanya, GreerAlisha, NaplesJames G, UpadhyeSuneel, EdlowJonathan A

BPPV treatment
No symptom resolution
Uncertain side effects

Vestibular suppressants may have no effect on symptom resolution at the point of longest follow-up in patients with BPPV, while canalith repositioning maneuvers (CRMs) may be superior.

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

14.

Pharmacological interventions for persistent postural-perceptual dizziness (PPPD).

Author: WebsterKatie E, Harrington-BentonNatasha A, JuddOwen, KaskiDiego, MaarsinghOtto R, MacKeithSamuel, RayJaydip, Van VugtVincent A, BurtonMartin J

PPPD symptom relief

This systematic review aims to evaluate the benefits and harms of pharmacological interventions for persistent postural-perceptual dizziness (PPPD), a chronic balance disorder characterized by subjective unsteadiness or dizziness that is worse on standing and with visual stimulation.

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

15.

Non-pharmacological interventions for persistent postural-perceptual dizziness (PPPD).

Author: WebsterKatie E, KamoTomohiko, SmithLaura, Harrington-BentonNatasha A, JuddOwen, KaskiDiego, MaarsinghOtto R, MacKeithSamuel, RayJaydip, Van VugtVincent A, BurtonMartin J

PPPD symptom relief

This systematic review aims to assess the benefits and harms of non-pharmacological interventions for persistent postural-perceptual dizziness (PPPD), a chronic balance disorder characterized by subjective unsteadiness or dizziness that is worse on standing and with visual stimulation.

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

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