Effective treatment of gastroenteritis: A Synthesis of Findings from 14 Studies

  1. Home
  2. Effective treatment of gastroenteritis
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Effective treatment of gastroenteritis: A Synthesis of Findings from 14 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Effective treatment of gastroenteritis: A Synthesis of Findings from 14 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Major Research Findings

There are various treatments for gastroenteritis, and the most effective approach can vary depending on factors such as age, symptoms, and severity. Several studies have explored the effectiveness and safety of different treatment options.

For instance, a study ( 14 ) found that a combination of probiotics and zinc was significantly more effective in treating acute gastroenteritis in children compared to dietary recommendations alone, probiotics alone, or zinc alone.

However, another study ( 8 ) showed that zinc treatment for acute gastroenteritis in children living in regions with rare zinc deficiency did not demonstrate significant benefits.

Furthermore, a study ( 9 ) investigated the effectiveness of ondansetron and domperidone for relieving vomiting symptoms in children with acute gastroenteritis and found both medications to be beneficial.

While these studies suggest several potentially effective treatments for gastroenteritis, the most suitable approach can vary depending on individual patient circumstances.

Treatment Summary

Here are some of the primary treatment options for acute gastroenteritis:

Benefits and Risks

Benefit Summary

Treating gastroenteritis aims to alleviate symptoms, prevent dehydration, and shorten recovery time.

Risk Summary

Gastroenteritis treatments can come with potential side effects. For instance, probiotics might cause digestive discomfort in some individuals. Excessive zinc intake can lead to side effects like nausea and vomiting. Oral rehydration therapy can result in electrolyte imbalances if not administered in the right amounts. Intravenous fluid therapy carries a risk of infection. Antiemetics may cause drowsiness or dizziness as side effects. Antibiotics can contribute to the emergence of antibiotic-resistant bacteria. Nitazoxanide can cause side effects such as headaches and nausea.

Comparison Across Studies

Similarities

Multiple studies consistently demonstrate the effectiveness of oral rehydration therapy in treating dehydration related to gastroenteritis. Additionally, research suggests that probiotics and zinc may contribute to symptom improvement in gastroenteritis.

Differences

The optimal treatment for gastroenteritis can vary depending on the patient's age, symptoms, and severity. Consequently, study results may show some variability. For example, the effectiveness of zinc treatment has been shown to differ based on the presence or absence of zinc deficiency.

Consistency and Discrepancies of Findings

Research findings regarding the effectiveness of gastroenteritis treatments exhibit some variability. This can be attributed to differences in study participant age, symptoms, severity, treatments used, and study design. Therefore, a cautious approach is necessary when interpreting these results.

Practical Considerations and Precautions

If you experience gastroenteritis symptoms, prioritize oral rehydration therapy. If your symptoms don't improve, consult a healthcare professional for appropriate treatment. Avoid self-medicating or discontinuing treatment without medical advice.

Current Limitations of Research

Further research on the effectiveness of gastroenteritis treatments remains necessary. In particular, long-term effects and potential side effects require more in-depth investigation.

Future Research Directions

Future research should delve deeper into the effectiveness and safety of gastroenteritis treatments. More precise studies, considering factors like patient age, symptoms, and severity, are needed. Additionally, gathering more data on long-term effects and potential side effects is crucial.

Conclusion

Gastroenteritis affects countless individuals worldwide. With appropriate treatment, symptoms usually improve. However, the ideal treatment for gastroenteritis can vary depending on the patient's age, symptoms, and severity. Therefore, it is essential to seek medical attention for appropriate diagnosis and treatment.

Treatment List

Oral rehydration therapy, probiotics, zinc, antiemetics, antibiotics, nitazoxanide

Literature analysis of 14 papers
Positive Content
10
Neutral Content
4
Negative Content
0
Article Type
9
4
5
4
14
1.

Effects of immediate modified feeding on infantile gastroenteritis.

Author: HoghtonM A, MittalN K, SandhuB K, MahdiG

Improved nutritional status
Gastroenteritis complications

This study reviewed the practice of withholding food from infants with acute gastroenteritis and dehydration. It suggests that immediate modified feeding, while on oral rehydration therapy (ORT), may be beneficial, especially for children who are already malnourished.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

2.

Single-dose quinolone treatment in acute gastroenteritis.

Author: ZamirDoron, WeilerZeev, KoganElena, Ben-ValidEli, HayEmile, ReitblatTatiana, PolishchukIlia

Diarrhea treatment

The study discussed the use of empiric antibiotic therapy in acute gastroenteritis in Israel, noting the need for more definitive diagnostic criteria and shorter antibiotic regimens.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

3.

Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children.

Author: HartlingL, BellemareS, WiebeN, RussellK, KlassenT P, CraigW

Shorter hospital stays
Paralytic ileus
Treatment failure

Oral rehydration therapy (ORT) was associated with a higher risk of paralytic ileus compared to intravenous rehydration therapy (IVT). However, IVT is associated with risks of intravenous therapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

4.

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.

Author: AlhashimiD, AlhashimiH, FedorowiczZ

Improved vomiting treatment
Vomiting

Vomiting from stomach flu is common in children and teens. Treating vomiting in children can be challenging, and the use of anti-nausea medications (antiemetics) is still debated due to concerns about side effects, such as drowsiness and movement problems, associated with older anti-nausea drugs.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

5.

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.

Author: AlhashimiD, AlhashimiH, FedorowiczZ

Improved vomiting treatment
Vomiting

Vomiting from stomach flu is common in children and teens. Treating vomiting in children can be challenging, and the use of anti-nausea medications (antiemetics) is still debated due to concerns about side effects, such as drowsiness and movement problems, associated with older anti-nausea drugs.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

6.

Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.

Author: RossignolJ-F, El-GoharyY M

Reduced time to symptom resolution

Nitazoxanide was more effective than placebo in reducing the time to resolution of symptoms in adults and adolescents with viral gastroenteritis caused by norovirus or rotavirus.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents.

Author: AlhashimiDunia, Al-HashimiHakima, FedorowiczZbys

Extrapyramidal reactions
Sedation

Vomiting from stomach flu is common in children and teens. Treating vomiting in children can be challenging, and the use of anti-nausea medications (antiemetics) is still debated due to concerns about side effects, such as drowsiness and movement problems, associated with older anti-nausea drugs.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

8.

Oral zinc for the treatment of acute gastroenteritis in Polish children: a randomized, double-blind, placebo-controlled trial.

Author: PatroBernadeta, SzymańskiHenryk, SzajewskaHania

Zinc supplementation did not show any significant benefit in treating acute gastroenteritis (AGE) in children living in a country where zinc deficiency is rare.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

9.

Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial.

Author: MarchettiFederico, MaestroAlessandra, RovereFrancesca, ZanonDavide, ArrighiniAlberto, BertolaniPaolo, BibanPaolo, Da DaltLiviana, Di PietroPasquale, RennaSalvatore, GualaAndrea, MannelliFrancesco, PazzagliaAnna, MessiGianni, PerriFrancesco, RealeAntonino, UrbinoAntonio Francesco, VallettaEnrico, VitaleAntonio, ZangardiTiziana, TondelliMaria Teresa, ClavennaAntonio, BonatiMaurizio, RonfaniLuca

Vomiting treatment

Vomiting in children with acute gastroenteritis (AG) leads to dehydration and makes oral rehydration therapy (ORT) less effective. Doctors often use intravenous fluids (IV) for mild or moderate dehydration when vomiting is a major symptom. This study aims to evaluate the effectiveness of commonly used anti-vomiting medications, like domperidone, in treating vomiting in children with AG. The goal is to reduce the need for IV fluids, hospital stays, and hospital admissions.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

10.

Treatment of aseptic dogs with hemorrhagic gastroenteritis with amoxicillin/clavulanic acid: a prospective blinded study.

Author: UntererS, StrohmeyerK, KruseB D, Sauter-LouisC, HartmannK

Antibiotic resistance

Treatment with amoxicillin/clavulanic acid did not improve the clinical course or outcome of hemorrhagic gastroenteritis (HGE) in dogs that did not show signs of sepsis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

11.

Bimodal Release Ondansetron for Acute Gastroenteritis Among Adolescents and Adults: A Randomized Clinical Trial.

Author: SilvermanRobert A, HouseStacey L, MeltzerAndrew C, HahnBarry, LovatoLuis M, AvarelloJahn, MillerJoseph B, KalfusIra N, FathiReza, RadayGilead, PlasseTerry F, YanEric C

Nausea and vomiting relief

Vomiting from gastroenteritis (stomach flu) is often treated with anti-nausea medications given through a vein. If effective oral treatments were available, people might not need intravenous fluids or medications. Additionally, a long-lasting oral medication could provide longer relief from nausea and vomiting.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

12.

A Systematic Review and Meta-Analysis: The Effectiveness of Probiotics for Viral Gastroenteritis.

Author: AnsariFereshteh, PashazadehFariba, NourollahiElaheh, HajebrahimiSakineh, MunnZachary, PourjafarHadi

Viral gastroenteritis treatment

Probiotics demonstrated effectiveness in improving symptoms of viral gastroenteritis, shortening the duration of diarrhea and hospitalization in patients.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

13.

Association Between Diarrhea Duration and Severity and Probiotic Efficacy in Children With Acute Gastroenteritis.

Author: SchnadowerDavid, O'ConnellKaren J, VanBurenJohn M, VanceCheryl, TarrPhillip I, SchuhSuzanne, HurleyKatrina, RogersAlexander J, PoonaiNaveen, RoskindCindy G, BhattSeema R, GouinSerge, MahajanPrashant, OlsenCody S, PowellElizabeth C, FarionKen, SapienRobert E, ChunThomas H, FreedmanStephen B,

Probiotics did not demonstrate efficacy for treating childhood acute gastroenteritis, regardless of symptom duration or frequency before treatment initiation.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

14.

Evaluation of treatment in acute gastroenteritis: A comparative study.

Author: YalcinGulsen, DemirbasFatma, BacalanFatma, ToyEvin Bahar

Improved gastroenteritis

This comparative, prospective, double-blind, placebo-controlled study compared the efficacy of only dietary recommendations, zinc, probiotics, and combination therapies in children admitted with acute gastroenteritis. The efficiency of combined treatment with probiotics and zinc was found to be significantly better in the treatment of childhood acute gastroenteritis.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.