Effective treatment of health checkup: A Synthesis of Findings from 21 Studies

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Original Abstract of the Article

Major Research Findings

Multiple studies suggest that health checkups can be effective in the early detection of various diseases, potentially leading to appropriate treatment. For example, 8 suggests that early detection and proper treatment of diabetes could reduce the proportion of patients requiring treatment for diabetic retinopathy. Additionally, 13 indicates that early detection of hepatocellular carcinoma can improve survival rates.

However, further research is required regarding the effectiveness of specific tests and treatments within health checkups. For instance, 14 focuses on developing a machine learning model to predict the effectiveness of statin treatment. This model could potentially predict the effectiveness of statins for individual patients beforehand.

Treatment Summary

8 states that treatments for diabetic retinopathy include laser photocoagulation, intraocular injection, and vitrectomy.

21 indicates that desmopressin is used for the treatment of diabetes insipidus.

13 states that treatment for hepatocellular carcinoma is selected based on the Barcelona Clinic Liver Cancer (BCLC) stage.

14 mentions that statins are used for the treatment of hyperlipidemia.

Benefits and Risks

Benefit Summary

Health checkups can be beneficial in the early detection of various diseases, potentially leading to improved treatment outcomes. For example, early detection of diabetic retinopathy and hepatocellular carcinoma can potentially lead to better treatment results.

Risk Summary

Health checkups should consider potential risks associated with tests, including the possibility of misdiagnosis. Additionally, the results of a health checkup may lead to excessive anxiety and stress for some individuals.

Comparison Between Studies

Commonalities

Multiple studies share the common understanding that health checkups are beneficial in the early detection of various diseases. Additionally, appropriate treatment based on health checkup results may potentially slow disease progression and improve patient quality of life.

Differences

Each study focuses on different diseases and employs different analysis methods. Therefore, interpreting the research results requires careful consideration. For example, 8 analyzes the proportion of patients requiring treatment for diabetic retinopathy, while 13 analyzes the survival rate for hepatocellular carcinoma.

Consistency and Contradictions

While research indicates consistent results regarding the effectiveness of health checkups, there are aspects that require further investigation. For example, 14 describes the development of a machine learning model to predict the effectiveness of statin treatment. However, the accuracy and clinical utility of this model require further validation.

Applying Results in Real Life: Cautions

Health checkup results should be interpreted within the context of individual circumstances. It is crucial to remember that health checkups are primarily intended for early disease detection, and they do not guarantee disease prevention or cure. It is important to avoid excessive anxiety or overreaction to health checkup results.

Limitations of Current Research

Due to variations in target populations, study durations, and analysis methods, it can be challenging to directly compare research results related to health checkups. Moreover, there are ethical considerations and concerns about privacy protection when evaluating the effectiveness of health checkups.

Future Research Directions

To more accurately assess the effectiveness of health checkups, large-scale, long-term follow-up studies are needed. Research involving individuals with diverse health conditions and lifestyles can provide a more comprehensive evaluation of health checkup effectiveness.

Conclusion

Health checkups have the potential to play a significant role in the early detection of various diseases, potentially leading to appropriate treatment. However, health checkups are primarily intended for early disease detection and do not guarantee disease prevention or cure. Health checkup results should be interpreted based on individual circumstances. Further research is expected to deepen our understanding of the effectiveness of health checkups.

Treatment List

Laser photocoagulation, intraocular injection, vitrectomy, desmopressin, statin

Literature analysis of 21 papers
Positive Content
16
Neutral Content
2
Negative Content
3
Article Type
0
2
1
1
20
1.

Assessment of the use of vitamin C and E supplements concomitantly to antibiotic treatment against Helicobacter pylori: A systematic review and meta-analysis.

Author: Caicedo OchoaEdgar Yaset, Quintero MorenoCésar Orlando, Méndez FandiñoYardany Rafael, Sánchez FonsecaSofía Catalina, Cortes MottaHéctor Fabio, Guio GuerraSantiago Alejandro

Antibiotic treatment
No effect
Study biases

Supplementation with vitamin C and E in the antibiotic treatment against Helicobacter pylori had no effect on eradication rates.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

3.

[Prevalence, treatment, and control of cardiovascular disease risk factors among adults in Shiga Prefecture: analysis using the receipt and health checkup information database in Japan].

Author: MiyagawaNaoko, MurakamiYoshitaka, OkayamaAkira, KakunoFumihiko, MiuraKatsuyuki

Disease prevention
Strategic planning

This study calculated the prevalence, treatment, and control of lifestyle-related diseases, including hypertension, diabetes, and hyper-low-density lipoprotein (LDL)-cholesterolemia among adults aged ≥40 years in Japan.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : Japanese

7.

Prediction of the 4-Year Incidence Risk of Ischemic Stroke in Healthy Japanese Adults: The Fukushima Health Database.

Author: MaEnbo, OhiraTetsuya, MiyazakiMakoto, FukasawaMaiko, YoshimotoMasayo, SuzukiTomonori, FuruyamaAyako, KataokaMariko, YasumuraSeiji, HosoyaMitsuaki

IS risk prediction

A 4-year risk prediction model for ischemic stroke (IS) revealed a good performance for IS incidence, and risk scores could be used to estimate individual incidence risk of IS.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

8.

Different incidences of diabetic retinopathy requiring treatment since diagnosis according to the course of diabetes diagnosis: a retrospective cohort study.

Author: SugiyamaTakehiro, Yanagisawa-SugitaAyako, TanakaHirokazu, Ihana-SugiyamaNoriko, ImaiKenjiro, OhsugiMitsuru, UekiKohjiro, TamiyaNanako, KobayashiYasuki

Diabetic retinopathy management
Diabetic retinopathy risk

This retrospective cohort study assessed the risk of treatment-requiring diabetic retinopathy based on the course of diabetes diagnosis. Promptly starting antidiabetic medication after diagnosis, especially without recent health checkups, increased the risk.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

9.

Seeking Treatment Profile of Male Shift Workers With Hypertension and Diabetes.

Author: AdiNuri Purwito, NagataTomohisa, MoriKoji, KuboTatsuhiko, FujimotoKenji, OhtaniMakoto, OdagamiKiminori, NagataMasako, KajikiShigeyuki, FujinoYoshihisa, MatsudaShinya

Treatment delay

This retrospective cohort study investigated the likelihood of seeking treatment for hypertension and diabetes among male shift workers. Shift workers were less likely to seek treatment for hypertension and diabetes compared with day workers.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

10.

Attitudes and Factors Determining the Practice of Routine Medical Checkups in the People of Rawalpindi, Pakistan: A Cross-Sectional Study.

Author: FazalFaizan, ShahaniHiba Arshad, GondalMudassar Fiaz, TanveerUsama, HaiderMuhammad, Us SabahNoor, ShahzadFaizan, Ur RehmanMohammad Ebad

Early disease detection
Preventative care
Barriers to access
Lack of awareness

This study assessed public awareness of routine medical checkups (RMCs), exploring factors that encourage and prevent their practice.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

11.

A vanished gastric gastrointestinal stromal tumor.

Author: HonjoSarah, YamauchiSuguru, YoshimotoYutaro, JunChen, EgawaHiroki, KubotaAkira, TsudaKenki, YubeYukinori, KajiSanae, OritaHajime, FukunagaTetsu

Accurate diagnosis
GIST removal
Optimal care

LECS was successfully performed on a vanished gastric GIST, leading to an accurate diagnosis and optimal postoperative care. The tumor was found in the resected specimen, confirming the diagnosis of GIST with intermediate risk.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

12.

Relationship between tinnitus and olfactory dysfunction: audiovisual, olfactory, and medical examinations.

Author: KatayamaNaomi, YoshidaTadao, NakashimaTsutomu, ItoYasuki, TeranishiMasaaki, IwaseTakeshi, SugiuraSaiko, GotoKensuke, UchidaYasue, TakiYosuke, NakadaTakafumi, TadaAi, SuzukiHirokazu, NakanoYuta, ShimonoMariko, SajiNaoki, KogureAnna, ShimizuEmiko, SoneMichihiko, HamajimaNobuyuki

Sensory organ evaluation

This study investigated the relationship between tinnitus and olfactory test results. The study found that subjective smell dysfunction and poor smell test results were significantly associated with tinnitus complaints. Hearing and vision were associated even after adjusting for age and sex. These findings suggest that evaluating the mutual relationships among sensory organs is important when evaluating the influence of sensory dysfunctions on cognitive function.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

16.

Lymph node metastasis after endoscopic submucosal dissection of a superficial esophageal adenocarcinoma arising from the ectopic gastric mucosa of the cervical esophagus: A case report.

Author: ItoMamoru, DobashiAkira, KomoriMoe, SugimuraShun, AizawaDaisuke, TakahashiKeita, TanishimaYuichiro, SumiyamaKazuki

Lymph node metastasis

This case report describes a rare case of lymph node metastasis after endoscopic submucosal dissection of esophageal adenocarcinoma derived from ectopic gastric mucosa. The findings suggest that close follow-up or additional treatment may be necessary for patients with invasion into the muscularis mucosa, even after endoscopic submucosal dissection.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Language : English

19.

Network meta-analysis of glucose-lowering drug treatment regimens with the potential risk of hypoglycemia in patients with type 2 diabetes mellitus in terms of glycemic control and severe hypoglycemia.

Author: KodamaSatoru, FujiharaKazuya, IshiguroHajime, MatsubayashiYasuhiro, KitazawaMasaru, IwanagaMidori, YamadaTakaho, KatoKiminori, NakagawaYoshimi, TanakaShiro, ShimanoHitoshi, SoneHirohito

Glycemic control
Hypoglycemia

This network meta-analysis aims to determine the optimal glucose-lowering drug treatment regimens for type 2 diabetes (T2D) patients in terms of glycemic control and severe hypoglycemia risk. The study finds that combining insulins with non-insulin glucose-lowering agents, excluding sulfonylurea or glinide, can improve glycemic control compared to insulins alone. The study also suggests that glinide plus thiazolidinedione and premixed insulin plus glucagon-like peptide-1 receptor agonist are promising combinations for achieving good glycemic control while minimizing the risk of severe hypoglycemia.

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

21.

Central diabetes insipidus with anti-rabphilin-3A antibody positivity causing hypovolemic shock after resection of tumorous lesions in the pelvic cavity.

Author: OhashiAtsuki, TakedaYuri, WatadaMizuki, IharaFumitaka, OshitaTadashi, IwataNaoko, FujisawaHaruki, SuzukiAtsushi, SugimuraYoshihisa, MaedaYoshitaka

Hormonal replacement therapy
Hypovolemic shock
Polyuria

This case report describes a 36-year-old woman who developed central diabetes insipidus (CDI) following surgery for uterine fibroids. After ruling out other causes, lymphocytic infundibuloneurohypophysitis (LINH) was suspected as the diagnosis. The patient successfully managed her CDI with nasal desmopressin. The report emphasizes the importance of considering anti-rabphilin-3A antibody testing in cases of idiopathic CDI.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

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