Side Effects of inclisiran injection: A Synthesis of Findings from 1 Studies

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Original Abstract of the Article

Major Research Findings

A study examining long-term imipramine treatment for panic disorder found that even after 6 months of successful treatment, patients continued to experience side effects like tachycardia, dry mouth, and sweating.

Reasons for Side Effects

Imipramine works by adjusting the activity of neurotransmitters like serotonin and norepinephrine, which helps reduce panic attacks. However, these neurotransmitters also play a role in various bodily functions, leading to potential side effects from imipramine.

Common Side Effects

Tachycardia

Imipramine can cause an increased heart rate due to its effect on the heart.

Dry Mouth

Imipramine can inhibit saliva production, resulting in dry mouth.

Sweating

Imipramine can increase sweating.

Weight Gain

Imipramine can lead to weight gain as it may increase appetite.

Sexual Dysfunction

Imipramine can suppress sexual function, potentially causing sexual dysfunction.

Side Effect Management

Tachycardia

If you experience tachycardia, consult with your doctor.

Dry Mouth

To manage dry mouth, drink plenty of fluids throughout the day.

Sweating

Choose breathable clothing to help with sweating.

Weight Gain

For weight gain concerns, talk to your doctor to explore appropriate dietary and exercise strategies.

Sexual Dysfunction

If sexual dysfunction occurs, discuss it with your doctor.

Comparison of Studies

Similarities

Multiple studies indicate that imipramine is effective for treating panic disorder. However, long-term treatment should involve careful monitoring for side effects.

Differences

The frequency and severity of side effects from imipramine can vary between studies. This may be attributed to differences in participant characteristics, dosages, and study design.

Application in Real Life: Cautions

While imipramine is a beneficial medication for panic disorder, it's crucial to understand the potential for side effects. Discuss the risks and benefits with your doctor before starting treatment.

Limitations of Current Research

Research on imipramine side effects is still ongoing. More studies are needed, especially regarding the frequency and severity of side effects in long-term treatment.

Future Research Directions

Future research should focus on investigating the long-term frequency and severity of imipramine side effects. Developing new treatment strategies for mitigating side effects is also essential.

Conclusion

Imipramine can be an effective treatment for panic disorder, but it's important to be aware of the potential side effects. Discuss these risks and benefits with your doctor before starting treatment.

Literature analysis of 1 papers
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Specific side effects of long-term imipramine management of panic disorder.

Author: MavissakalianMatig, PerelJames, GuoShenyang

Panic disorder treatment
Dry mouth
Sexual dysfunction
Sweating
Tachycardia
Weight gain

Imipramine, an antidepressant, is effective for panic disorder, but can cause side effects like dry mouth, sweating, and weight gain.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

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