Effective treatment of infections: A Synthesis of Findings from 1 Studies

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Original Abstract of the Article

Main findings

A review of 12 trials involving 778 participants (at least 258 infants and children) found no significant difference in illness duration, diarrhea, or fever between any antibiotic regimen and placebo in otherwise healthy children and adults with non-severe salmonella diarrhea. 1

Treatment Summary

This review found no evidence of a clinical benefit of antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Benefits and risks

Benefit Summary

This review found no evidence of a clinical benefit of antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Risk Summary

Antibiotics appear to increase adverse effects and they also tend to prolong salmonella detection in stools. 1

Comparison between studies

Commonalities of studies

This review found no evidence of a clinical benefit of antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Differences between studies

The review included studies with different antibiotic types, dosages, and patient demographics. 1

Consistency and contradictions of results

This review found consistent evidence that antibiotic therapy does not appear to be beneficial for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Precautions for applying to real life

Antibiotic therapy may not be beneficial for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Limitations of current research

The review included a limited number of studies. 1

Future research directions

Large-scale randomized controlled trials are needed to further assess the efficacy of antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Conclusion

This review found no evidence of a clinical benefit of antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

List of treatments

Antibiotic therapy for non-severe salmonella diarrhea in otherwise healthy children and adults. 1

Keywords
Benefit Keywords
Risk Keywords
Adverse effects
Prolonged salmonella
1
Literature analysis of 1 papers
Positive Content
0
Neutral Content
0
Negative Content
1
Article Type
0
0
1
1
1
1.

Antibiotics for treating salmonella gut infections.

Author: SirinavinS, GarnerP

Adverse effects
Prolonged salmonella

Antibiotic therapy does not appear to be clinically beneficial for otherwise healthy adults and children with non-severe salmonella diarrhea. Antibiotics may increase adverse effects and prolong salmonella detection in stools.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

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