Effective treatment of pregnancy and substance use: A Synthesis of Findings from 15 Studies

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Original Abstract of the Article

Main Research Findings

Maternal substance use during pregnancy is a common modifiable risk factor for poor birth outcomes, and is associated with long-term psychological risks to offspring. 2 Cognitive behavioral therapy and medication are being researched as treatments to help pregnant women stop using substances. 1 For the treatment of mental illnesses like schizophrenia, medication and cognitive behavioral therapy are known to be effective. 4 5 Early intervention may also have a positive impact on the course of mental illness. 7

Treatment Summary

Cognitive behavioral therapy is being considered as a treatment to help pregnant women stop using substances. 2 Medication and cognitive behavioral therapy are used to treat mental illnesses like schizophrenia. 4 5 8 Early intervention may be effective in treating mental illness, and it is important to combine medication with psychological therapy. 7

Benefits and Risks

Benefits Summary

Treatments for pregnant women who use substances may reduce the risk of poor birth outcomes and long-term psychological risks to offspring. 2 Early intervention is believed to be effective in treating mental illnesses. 7

Risks Summary

There are also risks associated with treatments for pregnant women who use substances, such as side effects from medications and questions regarding the effectiveness of psychological therapy. 2 For the treatment of mental illnesses, side effects from medications and resistance to treatment are concerns. 14

Comparison of Research

Similarities in Research

Many studies suggest that early intervention is crucial in the treatment of pregnant women who use substances or mental illness. 7 14

Differences in Research

Due to the variation in illnesses, treatment methods, and research design, it is essential to interpret results with caution.

Consistency and Contradictions in Results

There is no consistent evidence in some research regarding treatments for pregnant women who use substances or mental illness. 14 More research is required to reach more definitive conclusions.

Considerations for Real-Life Application

When treating pregnant women who use substances or mental illness, it is crucial to choose the right treatment based on individual circumstances. 2 14

Limitations of Current Research

Research into treatments for pregnant women who use substances or mental illness is limited by factors such as small sample sizes and short follow-up periods. 14

Future Research Directions

Larger and longer-term studies are needed for research into treatments for pregnant women who use substances or mental illness. 2 14

Conclusion

Early intervention is crucial in the treatment of pregnant women who use substances or mental illness. 7 14 Treatment methods and research designs vary greatly, so it is crucial to choose the right treatment for each individual. 2 14 We hope that larger studies and longer-term follow-ups will lead to the development of effective treatments in the future.

Treatment List

Cognitive behavioral therapy, medication, early intervention

Literature analysis of 15 papers
Positive Content
12
Neutral Content
1
Negative Content
2
Article Type
4
2
7
7
14
2.

Maternal self concept as a provider and cessation of substance use during pregnancy.

Author: MasseySuena H, NeiderhiserJenae M, ShawDaniel S, LeveLeslie D, GanibanJody M, ReissDavid

Substance use cessation

This study examined birth mothers who made adoption placements participating in the Early Growth and Development Study to investigate the relationship between self-concept as a provider and cessation of substance use during pregnancy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

3.

Disparity in posttraumatic stress disorder diagnosis among African American pregnant women.

Author: SengJulia S, Kohn-WoodLaura P, McPhersonMelnee D, SperlichMickey

Posttraumatic stress disorder
Trauma exposure

This study found that African American women expecting their first child are four times more likely to experience posttraumatic stress disorder (PTSD) than non-African American women. The higher prevalence of PTSD is linked to greater trauma exposure, suggesting that addressing traumatic stress may be crucial in reducing birth outcome disparities.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

4.

Depot flupenthixol decanoate for schizophrenia or other similar psychotic disorders.

Author: QuraishiS, DavidA

Lower relapse rate
Reduced movement disorders
Insufficient evidence

There is no clear evidence that flupenthixol decanoate is more effective than other depot antipsychotics for schizophrenia. Larger, well-designed trials are needed.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

5.

Depot fluspirilene for schizophrenia.

Author: QuraishiS, DavidA

Reduced movement disorders
Insufficient evidence

There is no convincing evidence that fluspirilene decanoate is more effective than oral chlorpromazine or other depot antipsychotics for schizophrenia. More research is needed to inform clinical practice.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

6.

Duration of untreated psychosis and its relationship to clinical outcome.

Author: NormanRoss M G, LewisShôn W, MarshallMax

Remission of positive symptoms
Correlational evidence
Neurotoxic effects

Evidence suggests that longer duration of untreated psychosis (DUP) is an independent predictor of poorer treatment outcome, particularly remission of positive symptoms. More research is needed to confirm causality.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

7.

[Early detection of psychotic disorders].

Author: SchäferMiriam R, KlierClaudia M, PapageorgiouKonstantinos, FriedrichMax H, AmmingerG Paul

Prevent psychosis
Reduce treatment delays

Early intervention programs for schizophrenia and other psychotic disorders are being established globally.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : German

8.

[Cognitive-behavioral group treatment for schizophrenia and other psychotic disorders- a systematic review].

Author: Mortan SeviOya, Tekinsav SütcüSerap

Decrease anxiety
Improve hopelessness
Reduce psychosis symptoms

Cognitive-behavioral therapies plus standard treatment are effective in decreasing the symptoms of schizophrenia and other psychotic disorders (positive and negative symptoms) and/or the problems that accompany the disorder (anxiety, hopelessness).

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : Turkish

9.

Changes in insight during treatment for psychotic disorders: a meta-analysis.

Author: PijnenborgGerdina H M, van DonkersgoedRozanne J M, DavidAnthony S, AlemanAndré

Improved insight

A meta-analysis of psychological and pharmacological treatments for psychosis found that these treatments can improve insight into illness.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

10.

First rank symptoms for schizophrenia.

Author: Soares-WeiserKarla, MaayanNicola, BergmanHanna, DavenportClare, KirkhamAmanda J, GrabowskiSarah, AdamsClive E

Psychotic disorders
Schizophrenia

Early and accurate diagnosis of schizophrenia is important for better long-term outcomes. Delaying treatment can lead to more severe symptoms and slower recovery. This study aims to determine whether specific symptoms, known as First Rank Symptoms (FRS), are helpful in distinguishing schizophrenia from other psychotic disorders, as there is uncertainty about how accurate these symptoms are in making diagnoses.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

11.

Cost effectiveness of interpersonal community psychiatric treatment for people with long-term severe non-psychotic mental disorders: protocol of a multi-centre randomized controlled trial.

Author: van VeenMark, KoekkoekBauke, MulderNiels, PostulartDebby, AdangEddy, TeerenstraSteven, SchoonhovenLisette, van AchterbergTheo

Cost reduction
Health gain

The study aims to improve the care for individuals with long-term non-psychotic psychiatric disorders. A new treatment model called Interpersonal Community Psychiatric Treatment (ICPT) is being compared to standard care.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

12.

Prolonged exposure and EMDR for PTSD v. a PTSD waiting-list condition: effects on symptoms of psychosis, depression and social functioning in patients with chronic psychotic disorders.

Author: de BontP A J M, van den BergD P G, van der VleugelB M, de RoosC, de JonghA, van der GaagM, van MinnenA M

EMDR effective
PE effective
Remission from schizophrenia

Prolonged exposure (PE) and eye movement desensitization and reprocessing (EMDR) reduced PTSD symptoms and paranoid thoughts in patients with chronic psychotic disorders. More patients in the PE and EMDR groups achieved remission from their psychotic disorder.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

13.

Cognitive behavioral therapy for social activation in recent-onset psychosis: Randomized controlled trial.

Author: PosKarin, FrankeNathalie, SmitFilip, WijnenBen F M, StaringAnton B P, Van der GaagMark, MeijerCarin, de HaanLieuwe, VelthorstEva, SchirmbeckFrederike

Improved psychotic disorder treatment

Negative symptoms in psychosis are difficult to treat and contribute to poor outcomes. A cognitive-behavioral approach has shown promise for people with chronic schizophrenia. This study investigates whether a combination of group and individual therapy focused on social engagement (CBTsa) could benefit people recently diagnosed with psychosis.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

15.

[Use of psychoactive substances as a treatment for psychosis].

Author: Serrano-JiménezE, de Lucas-MorenoM G

Psychotic disorder treatment

Psychotic disorders are long-term mental health problems. While medications are used to treat them, these drugs primarily focus on certain symptoms and have many side effects. We need new treatments that target other brain systems. This review will examine whether certain medications used for other conditions could be helpful in treating people with psychotic disorders.

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : Spanish

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