Effective treatment of rubella: A Synthesis of Findings from 17 Studies

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Original Abstract of the Article

Major Research Findings

Several studies have suggested the effectiveness of the measles, mumps, and rubella (MMR) vaccine in treating warts. Specifically, a study 15 compared the effectiveness of MMR vaccine treatment for warts to cryotherapy and found a higher complete response rate in the MMR vaccine group. Additionally, a study 11 suggests that MMR vaccine is a safe and effective treatment for anogenital warts. Another study 3 examined the effectiveness and side effects of MMR vaccine in treating warts and found that many patients experienced complete or partial responses to treatment.

Treatment Summary

The study 15 compared MMR vaccine to cryotherapy for treating warts. The study 11 used MMR vaccine to treat anogenital warts. The study 3 examined the effectiveness and side effects of MMR vaccine in treating warts.

Benefits and Risks

Benefits Summary

The MMR vaccine may be an effective treatment for warts. Specifically, a study 15 showed that MMR vaccine has a higher complete response rate than cryotherapy. Additionally, the MMR vaccine may also be an effective treatment for anogenital warts. 11

Risks Summary

Side effects of the MMR vaccine include pain, bleeding, flu-like symptoms, urticaria, cervical lymphadenopathy, and erythema multiforme. However, a study 3 found that side effects were generally mild and often resolved within a short period of time.

Comparison between Studies

Commonalities

Multiple studies have suggested the effectiveness of the MMR vaccine in treating warts.

Differences

Studies differed in the types of warts targeted, the comparison treatments used, the study design, and the sample size, requiring caution in interpreting results.

Consistency and Inconsistencies of Results

While several studies have suggested the effectiveness of MMR vaccine in treating warts, not all studies have yielded the same results. Further research is required to understand the effectiveness and safety of MMR vaccine in treating warts.

Implications for Real-Life Application

While the MMR vaccine may be effective in treating warts, it is not effective for everyone. Additionally, the risks of side effects should be considered. Consultation with a doctor before receiving MMR vaccine treatment is essential.

Limitations of Current Research

Research on MMR vaccine treatment for warts is still insufficient. Long-term effectiveness and safety studies are particularly limited. Additionally, variations in study design and size require caution when comparing results.

Future Research Directions

Research is needed to assess the long-term effectiveness and safety of MMR vaccine treatment for warts. It is also necessary to investigate whether MMR vaccine is superior to other treatments. Further research is needed to determine which types of warts MMR vaccine is effective for.

Conclusion

While the MMR vaccine may be an effective treatment for warts, it is not effective for everyone. Side effect risks should be considered. Consultation with a doctor before receiving MMR vaccine treatment is essential. Further research is expected to clarify the effectiveness and safety of the MMR vaccine in treating warts.

Treatment List

MMR vaccine, cryotherapy, salicylic acid-lactic paint, 5-fluorouracil, vitamin D3, Candida antigen, tuberculin purified protein derivative (PPD), nitazoxanide

Literature analysis of 17 papers
Positive Content
17
Neutral Content
0
Negative Content
0
Article Type
5
0
0
1
17
5.

Intralesional Measles, Mumps, Rubella Vaccine versus Tuberculin Purified Protein Derivative Injections in the Treatment of Palmoplantar and Periungual Warts: A Double-Blind Randomized Controlled Trial.

Author: RutninSuthinee, NamasondhiAmornrut, PomsoongCherrin, KositkuljornChaninan, AnuntrangseeTanaporn, ThadaniponKunlawat

Distant warts
High efficacy

Intralesional immunotherapy with measles, mumps, rubella vaccine (MMR) and tuberculin purified protein derivative (PPD) can be effective for palmoplantar and periungual warts. Further research is needed to compare the effects of these treatments and the role of dermoscopy in predicting treatment outcomes.

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

8.

Intralesional injection of Candida albicans antigen versus measles, mumps, and rubella vaccine for treatment of plantar warts.

Author: RagehRania Mahmoud, HewedyEl-Sayed Shaaban, HegabDoaa Salah

Candida albicans-specific antigen
Intralesional immunotherapy
MMR vaccine
Plantar warts
Wart recurrence

This study compared the efficacy of Candida albicans-specific antigen versus measles, mumps, and rubella (MMR) vaccine for treatment of plantar warts by intralesional injection.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

9.

Intralesional Measles, Mumps, and Rubella Vaccine Versus Intralesional <i>Candida</i> Antigen in the Treatment of Common and Plantar Warts.

Author: NofalAhmad, El-ArabReda Ezz, NasrMohamed, AlakadRania

Safe treatment
Wart clearance

This study evaluated the efficacy and safety of intralesional measles, mumps, and rubella (MMR) vaccine compared with intralesional Candida antigen in 68 patients with multiple common and plantar warts. The study found that intralesional MMR vaccine resulted in a higher therapeutic response rate and lower recurrence rate compared to intralesional Candida antigen.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

13.

A comparative study of the efficacy and safety of intralesional measles, mumps, and rubella vaccine versus intralesional vitamin D3 for the treatment of warts in children.

Author: MohtaAlpana, KushwahaRamesh Kumar, GautamUmesh, SharmaPritee, NyatiAsha, JainSuresh Kumar

Wart treatment

This article discusses the use of intralesional vitamin D3 and the measles, mumps, and rubella (MMR) vaccine as immunotherapies for cutaneous warts in children. Although both treatments have shown promise, further research is needed to determine their efficacy and safety in this population.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

15.

Intralesional injection of measles, mumps, and rubella vaccine versus cryotherapy in treatment of warts: A randomized controlled trial.

Author: Abd El-MagiudEnsaf M, Abd El-SameaGehad M, GaberHisham D

MMR vaccine
Wart treatment

Intralesional injection of measles, mumps, and rubella (MMR) vaccine was found to be a safe and effective treatment for multiple common and plantar warts compared to cryotherapy. While complete response rates were higher in the MMR group (70%) compared to the cryotherapy group (45%), the difference was not statistically significant. However, partial response was significantly higher in the cryotherapy group.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

16.

The Efficacy and Safety of Intralesional Immunotherapy with Measles, Mumps, Rubella Virus Vaccine for the Treatment of Common Warts in Adults.

Author: ChauhanPushpinder Singh, MahajanVikram K, MehtaKaraninder Singh, RawatRitu, SharmaVikas

Effective wart treatment
Low recurrence
Injection site pain

Intralesional MMR vaccine immunotherapy appears to be another possible safe and effective treatment option for common warts in a set of adult patients.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

17.

Outcomes for Nitazoxanide Treatment in a Case Series of Patients with Primary Immunodeficiencies and Rubella Virus-Associated Granuloma.

Author: PerelyginaLudmila, BuchbinderDavid, DorseyMorna J, EloitMarc, HauckFabian, HautalaTimo, MoshousDespina, UriarteIgnacio, DeripapaElena, IcenogleJoseph, SullivanKathleen E

Rubella treatment

The drug nitazoxanide has shown in vitro effectiveness against the rubella virus. This study aims to assess the in vivo effectiveness of nitazoxanide therapy in patients with immunodeficiency-related vaccine-derived rubella.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Language : English

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