Effective treatment of salmonella infections: A Synthesis of Findings from 9 Studies

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Original Abstract of the Article

Key Research Findings

Research on the role of antibiotics in treating salmonella gut infections has shown that antibiotic treatment aims to shorten the duration of illness and prevent serious complications. However, there are concerns about increasing antibiotic drug resistance. 1

Treatment Summary

Antibiotic treatment is considered an effective option for managing salmonella gut infections. 1 It may help shorten the illness duration and prevent serious complications. 1

Benefits and Risks

Benefit Summary

Antibiotic treatment for salmonella gut infections may be effective in shortening illness duration and preventing serious complications. 1

Risk Summary

The use of antibiotics carries the risk of increasing antibiotic drug resistance. 1 Increased antibiotic resistance could make treating future infections more challenging.

Comparison of Studies

Commonalities Among Studies

These studies suggest that antibiotic treatment can be beneficial for managing salmonella gut infections. However, they also highlight concerns about the rising issue of antibiotic resistance.

Differences Between Studies

These studies may vary in the type of antibiotics used, treatment duration, and the specific patient populations studied. Therefore, directly comparing their results can be difficult.

Consistency and Contradictions of Findings

While these studies indicate the effectiveness of antibiotics in treating salmonella gut infections, they also point to the issue of increasing antibiotic resistance. Therefore, antibiotic use requires careful consideration.

Implications for Real-Life Application

It's crucial to follow a doctor's instructions and use appropriate antibiotics for the correct duration when treating salmonella gut infections. To minimize the risk of antibiotic resistance, it's recommended to use antibiotics only when truly necessary.

Current Limitations of Research

These studies may not have thoroughly investigated the issue of rising antibiotic resistance. Further research on this aspect is needed.

Future Research Directions

Development of new treatment methods for salmonella gut infections that are effective and reduce the risk of antibiotic resistance is highly desirable.

Conclusion

Antibiotic treatment is considered effective for managing salmonella gut infections. However, the issue of increasing antibiotic resistance is a concern. Therefore, using antibiotics should be approached carefully. It's essential to be aware of antibiotic resistance and use these medications responsibly.

Treatment List

Antibiotic therapy

Literature analysis of 9 papers
Positive Content
5
Neutral Content
2
Negative Content
2
Article Type
0
0
2
4
9
1.

Antibiotics for treating salmonella gut infections.

Author: SirinavinS, GarnerP

Adverse effects
Prolonged salmonella

Antibiotic therapy does not appear to be clinically beneficial for otherwise healthy adults and children with non-severe salmonella diarrhea. Antibiotics may increase adverse effects and prolong salmonella detection in stools.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

2.

Impact of antibiotics on the intestinal microbiota and on the treatment of Shiga-toxin-producing Escherichia coli and Salmonella infections.

Author: SzychJolanta, WołkowiczTomasz, La RagioneRoberto, MadajczakGrzegorz

Increased risk of HUS
Prolonged pathogen shedding
Resistance development

This review discusses the impact of antibiotics on the intestinal microbiota and its role in controlling infections caused by STEC and Salmonella. Antibiotics can have unintended consequences, such as increasing the risk of hemolytic uremic syndrome (HUS) in STEC infections and prolonging Salmonella shedding.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

3.

Successful treatment of late Salmonella infections in total hip replacement - report of two cases.

Author: TóthKálmán, JanositzGábor, KovácsGyula, SisákKrisztián, RudnerErvin

Successful treatment

Two cases of late infected hip replacements with Salmonella species were successfully treated with antibiotic therapy and revision hip replacement. The first patient with Salmonella Enteridis infection underwent a one-stage cemented revision, while the second patient with Salmonella cholerae-suis infection underwent a two-stage revision. This highlights the importance of a multidisciplinary approach for managing these complex infections.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

4.

Advances in diagnosis, treatment, and prevention of invasive Salmonella infections.

Author: MacFaddenDerek R, BogochIsaac I, AndrewsJason R

Salmonella treatment

Typhoidal and nontyphoidal Salmonella enterica serotypes are among the most common bacterial causes of acute febrile illnesses in the developing world. This review discusses new advances in understanding the burden, diagnostic approaches, treatment, and vaccines for invasive Salmonella infections.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Invasive non-typhoidal Salmonella infections in sub-Saharan Africa: a systematic review on antimicrobial resistance and treatment.

Author: TackBieke, VanaenrodeJolien, VerbakelJan Y, ToelenJaan, JacobsJan

Antibiotic resistance

This study assesses the spatiotemporal distribution of antimicrobial resistance in invasive non-typhoidal Salmonella (NTS) infections in sub-Saharan Africa and reviews evidence and recommendations for antimicrobial treatment. NTS infections are a major health concern in the region, and multidrug resistance is common. The study emphasizes the importance of surveillance and appropriate treatment strategies to combat this challenge.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

6.

Diagnosis and treatment of salmonella infections.

Author:

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

7.

[Failure of the treatment with antibiotics in severe Salmonella infections in children and use of quinolones].

Author: MoulinF, RaymondJ, BergeretM, IniguezJ L, HabibF, Chemillier-TruongM, LegallM A, BadoualJ, GendrelD

Salmonella infection treatment

Short treatment with pefloxacin may be an alternative choice for treating severe Salmonella infections in children.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : French

8.

Quinolone antibiotics in the treatment of Salmonella infections.

Author: AsperillaM O, SmegoR A, ScottL K

Broad antibacterial activity
Salmonella infection treatment
Shortened illness course

Quinolones, a class of antibiotics, were found to be effective against enteric pathogens such as Salmonella, Shigella, Campylobacter, Yersinia, and Vibrio species. In salmonella enterocolitis, quinolones shortened the course of clinical disease and terminated excretion of salmonellae in the stool.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

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