著者: Levy-CoopermanN, McIntyreG, BonifacioL, McDonnellM, DavenportJ M, CovingtonP S, DoveL S, SellersE M

原題: Abuse Potential and Pharmacodynamic Characteristics of Oral and Intranasal Eluxadoline, a Mixed μ- and κ-Opioid Receptor Agonist and δ-Opioid Receptor Antagonist.

著者: LemboAnthony J, CovingtonPaul S, DoveLeonard S, AndraeDavid A

原題: Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials.

著者: AnwerMd Khalid, AhmedMohammed Muqtader, AldawsariMohammed F, IqbalMuzaffar, SolimanGamal A, AljuffaliIbrahim A

原題: Eluxadoline-Loaded Eudragit Nanoparticles for Irritable Bowel Syndrome with Diarrhea: Formulation, Optimization Using Box-Behnken Design, and Anti-Diarrheal Activity.

著者: BoinpallyRamesh, McGeeneyDanielle, KaczynskiEdward, WeissmanDarren

原題: An Open-Label Study to Evaluate the Effect of Eluxadoline on the Single-Dose Pharmacokinetics of Midazolam in Healthy Participants.

著者: QinDi, TaoQing-Feng, HuangShi-Le, ChenMin, ZhengHui

原題: Eluxadoline Versus Antispasmodics in the Treatment of Irritable Bowel Syndrome: An Adjusted Indirect Treatment Comparison Meta-analysis.

著者: VijayvargiyaPriya, Breen-LylesMargaret, NordSara Linker, MaselliDaniel, BusciglioIrene, BoinpallyRamesh, MuslinAnna, CarrothersTimothy J, CamilleriMichael

原題: Safety and Efficacy of Eluxadoline in Patients with Irritable Bowel Syndrome-Diarrhea With or Without Bile Acid Diarrhea: Open-Label Study.

著者: WechslerEmily V, ShahEric D

原題: Diarrhea-Predominant and Constipation-Predominant Irritable Bowel Syndrome: Current Prescription Drug Treatment Options.

著者: LiXia, LiBo, ZhangJiaqi, ChenTing, WuHaomeng, ShiXiaoshuang, MaJinxin, QinJinyan, TangXudong, WangFengyun

原題: Efficacy of opioid receptor modulators in patients with irritable bowel syndrome: A systematic review and meta-analysis.

著者: MarucaAnnalisa, LupiaAntonio, RoccaRoberta, KeszthelyiDaniel, CorsettiMaura, AlcaroStefano

原題: In Silico Food-Drug Interaction: A Case Study of Eluxadoline and Fatty Meal.

著者: MousaviTaraneh, NikfarShekoufeh, AbdollahiMohammad

原題: An update on efficacy and safety considerations for the latest drugs used to treat irritable bowel syndrome.

著者: LiuRebecca, StallerKyle

原題: Update on Eluxadoline for the Treatment of Irritable Bowel Syndrome with Diarrhea: Patient Selection and Perspectives.

著者: DiCelloJesse J, CarboneSimona E, SaitoAyame, RajasekharPradeep, CeredigRhian A, PhamVi, ValantCeline, ChristopoulosArthur, VeldhuisNicholas A, CanalsMeritxell, MassotteDominique, PooleDaniel P

原題: Mu and Delta Opioid Receptors Are Coexpressed and Functionally Interact in the Enteric Nervous System of the Mouse Colon.

著者: BrennerDarren M, SayukGregory S

原題: Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea.

著者: ShahidZainab, PackardElizabeth, GroffAndrew, JainRohit

原題: Eluxadoline-induced pancreatitis occurring in an adult man without a prior cholecystectomy.

著者: SaffouriGeorge B, Shields-CutlerRobin R, ChenJun, YangYi, LekatzHeather R, HaleVanessa L, ChoJanice M, BattaglioliEric J, BhattaraiYogesh, ThompsonKevin J, KalariKrishna K, BeheraGaurav, BerryJonathan C, PetersStephanie A, PatelRobin, SchuetzAudrey N, FaithJeremiah J, CamilleriMichael, SonnenburgJustin L, FarrugiaGianrico, SwannJonathan R, GroverMadhusudan, KnightsDan, KashyapPurna C

原題: Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders.

著者: BlackChristopher J, BurrNicholas E, CamilleriMichael, EarnestDavid L, QuigleyEamonn Mm, MoayyediPaul, HoughtonLesley A, FordAlexander C

原題: Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: systematic review and network meta-analysis.

著者: CorsettiMaura, PannemansJasper, WhorwellPeter

原題: Targeting mu opioid receptors to modulate gastrointestinal function: what have we learnt so far from the studies in functional bowel disorders?

著者: OldenKevin W, CheyWilliam D, ShringarpureReshma, Paul NicandroJean, ChuangEmil, EarnestDavid L

原題: Alosetron versus traditional pharmacotherapy in clinical practice: effects on resource use, health-related quality of life, safety and symptom improvement in women with severe diarrhea-predominant irritable bowel syndrome.

著者: AbelJessica L, CarsonRobyn T, AndraeDavid A

原題: The impact of treatment with eluxadoline on health-related quality of life among adult patients with irritable bowel syndrome with diarrhea.

著者: LacyBrian E

原題: Review article: an analysis of safety profiles of treatments for diarrhoea-predominant irritable bowel syndrome.

著者: PannemansJ, CorsettiM

原題: Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?

著者: ZhengYi, ObengSamuel, WangHuiqun, StevensDavid L, KomlaEssie, SelleyDana E, DeweyWilliam L, AkbaraliHamid I, ZhangYan

原題: Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.

著者: ZhuLingping, MaYunhui, YeShasha, ShuZhiqun

原題: Acupuncture for Diarrhoea-Predominant Irritable Bowel Syndrome: A Network Meta-Analysis.

著者: SimrénMagnus, TackJan

原題: New treatments and therapeutic targets for IBS and other functional bowel disorders.

著者: ChhapariaAnuj, HammamiMuhammad B, VareedayahAshley, SchroederKatie

原題: Eluxadoline-Associated Pancreatitis in a Post-Cholecystectomy Patient: A Case Report.

著者: BonifacioLaura, HuntThomas L, McIntyreGail, DoveLeonard S, CovingtonPaul S

原題: Evaluation of Eluxadoline Effect on Cardiac Repolarization.

著者: DothelGiovanni, BarbaroMaria Raffaella, RaschiEmanuel, BarbaraGiovanni, De PontiFabrizio

原題: Advancements in drug development for diarrhea-predominant irritable bowel syndrome.

著者: HarinsteinL, WuE, BrinkerA

原題: Postmarketing cases of eluxadoline-associated pancreatitis in patients with or without a gallbladder.

著者: ÖzdenerAyşe Elif, RivkinAnastasia

原題: Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome.