著者: IstifliErman Salih, OkumusNurullah, SarikurkcuCengiz, KuhnEduardo Ramires, NetzPaulo A, TepeArzuhan Sihoglu

原題: Comparative docking and molecular dynamics studies of molnupiravir (EIDD-2801): implications for novel mechanisms of action on influenza and SARS-CoV-2 protein targets.

著者: TortiCarlo, OlimpieriPier Paolo, BonfantiPaolo, TasciniCarlo, CelantSimone, TacconiDanilo, NicastriEmanuele, TacconelliEvelina, CacopardoBruno, PerrellaAlessandro, BuccolieroGiovanni Battista, ParrutiGiustino, BassettiMatteo, BiagettiCarlo, GiacomettiAndrea, ErneElke Maria, FrontutoMaria, LanzafameMassimiliano, SummaValentina, SpagnoliAlessandra, VestriAnnarita, Di PerriGiovanni, RussoPierluigi, PalùGiorgio

原題: Real-life comparison of mortality in patients with SARS-CoV-2 infection at risk for clinical progression treated with molnupiravir or nirmatrelvir plus ritonavir during the Omicron era in Italy: a nationwide, cohort study.

著者: BihorelSébastien, CaoYoufang, ChawlaAkshita, BirgerRuthie, MaasBrian M, GaoWei, RoepckeStefan, SardellaSusanne, HumphreyRebecca, KondraguntaSindhuri, JayaramanBhuvana, MartinhoMonika, PainterWendy, PainterGeorge, HolmanWayne, De AndaCarisa, BrownMichelle L, JohnsonMatthew G, PaschkeAmanda, RizkMatthew L, StoneJulie A

原題: Population pharmacokinetics of molnupiravir in adults with COVID-19: Lack of clinically important exposure variation across individuals.

著者: BakosÉva, Temesszentandrási-AmbrusCsilla, Özvegy-LaczkaCsilla, GáborikZsuzsanna, SarkadiBalázs, TelbiszÁgnes

原題: Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters.

著者: ChavdaVivek P, TeliDivya, BalarPankti C, VaghelaDixa, SolankiHetvi K, VaishnavAkta, VoraLalitkumar

原題: Potential Anti-SARS-CoV-2 Prodrugs Activated by Phosphorylation and Their Role in the Aged Population.

著者: RabieAmgad M, EltaybWafa A

原題: Potent Dual Polymerase/Exonuclease Inhibitory Activities of Antioxidant Aminothiadiazoles Against the COVID-19 Omicron Virus: A Promising In Silico/In Vitro Repositioning Research Study.

著者: GaoYa, LiuMing, LiZhifan, XuJianguo, ZhangJunhua, TianJinhui

原題: Molnupiravir for treatment of adults with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials.

著者: AkazawaDaisuke, OhashiHirofumi, HishikiTakayuki, MoritaTakeshi, IwanamiShoya, KimKwang Su, JeongYong Dam, ParkEun-Sil, KataokaMichiyo, ShionoyaKaho, MifuneJunki, TsuchimotoKana, OjimaShinjiro, AzamAa Haeruman, NakajimaShogo, ParkHyeongki, YoshikawaTomoki, ShimojimaMasayuki, KigaKotaro, IwamiShingo, MaedaKen, SuzukiTadaki, EbiharaHideki, TakahashiYoshimasa, WatashiKoichi

原題: Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments.

著者: YangBo, LiuChao, JuXiaohui, WuBingbing, WangZhuangfei, DongFucheng, YuYanying, HouXiaohui, FangMin, GaoFei, GuoXuejiang, GuiYaoting, DingQiang, LiWei

原題: A tissue specific-infection mouse model of SARS-CoV-2.

著者:

原題: Molnupiravir provides little benefit in vaccinated adults with COVID-19.

著者: BossKristina, KonikMargarethe, BräsenJan Hinrich, SchmitzJessica, JürgensChristiane, KribbenAndreas, WitzkeOliver, DolffSebastian, GäcklerAnja

原題: COVID-19 associated acute transplant failure after AB0-incompatible living donor kidney transplantation - a case report.

著者: OrthHans Martin, FlasshoveCharlotte, BergerMoritz, HattenhauerSandra Tessa, BiederbickKaja D, MispelbaumRebekka, KleinUwe, StemlerJannik, FisahnMatthis, DoleschallAnna D, BaermannBen-Niklas, KoenigshausenEva, TselikmannOlga, KillerAlexander, de AngelisClara, GligaSmaranda, StegbauerJohannes, SpuckNikolai, SillingGerda, RockstrohJürgen K, StrassburgChristian P, BrossartPeter, PanseJens P, JensenBjörn-Erik Ole, LueddeTom, BoeseckeChristoph, HeineAnnkristin, CornelyOliver A, MoninMalte B

原題: Early combination therapy of COVID-19 in high-risk patients.

著者: LinYun, WuPeng, TsangTim K, WongJessica Y, LauEric H Y, YangBingyi, LeungGabriel M, CowlingBenjamin J

原題: Viral kinetics of SARS-CoV-2 following onset of COVID-19 in symptomatic patients infected with the ancestral strain and omicron BA.2 in Hong Kong: a retrospective observational study.

著者: CheungYue Yat Harrison, LauEric Ho Yin, YinGuosheng, LinYun, CowlingBenjamin J, LamKwok Fai

原題: Effectiveness of Vaccines and Antiviral Drugs in Preventing Severe and Fatal COVID-19, Hong Kong.

著者: ZhangYumin, SunYuan, XieYuanchao, ShangWeijuan, WangZhen, JiangHualiang, ShenJingshan, XiaoGengfu, ZhangLeike

原題: A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir.