Paper Details

  1. Home
  2. Paper Details

A pilot study on the motor effects of rimantadine in Parkinson's disease.

Author: AdlerC H, CavinessJ N, EvidenteV G, Gwinn-HardyK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Rimantadine showed potential antiparkinsonian properties in a pilot study, with improvement in Hoehn and Yahr staging and motor scores.
Paper Details　
Original Abstract of the Article :
The purpose of this pilot study was to determine whether rimantadine, the alpha-methyl derivative of amantadine, might have any antiparkinsonian properties. In an open-label trial, 14 patients (12 de novo and 2 on levodopa treatment) with Hoehn and Yahr stage 2 to 3 Parkinson's disease were placed o...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1097/00002826-199901000-00006

データ提供：米国国立医学図書館（NLM）

Rimantadine: A Potential Oasis for Parkinson's Disease

This research delves into the realm of Parkinson's disease, investigating the potential of rimantadine, a drug related to amantadine, as a treatment option. The authors conducted a pilot study to assess the motor effects of rimantadine in patients with Parkinson's disease.

A Promising Glimpse: Rimantadine Shows Motor Benefits

Their findings indicate that rimantadine demonstrated some motor benefits in patients with Parkinson's disease, improving their overall motor function and reducing rigidity. This finding, like a shimmering oasis in the desert, offers hope for new treatment options for this debilitating condition.

A Need for Further Exploration: A Double-Blind Study

The study emphasizes the need for a larger, double-blind, placebo-controlled study to confirm these initial findings. This next step, like venturing deeper into the desert to uncover hidden treasures, will provide more definitive evidence of rimantadine's effectiveness.

Dr.Camel's Conclusion

This pilot study, like a trailblazer venturing into uncharted territory, suggests that rimantadine may hold promise as a potential treatment option for Parkinson's disease. While further research is needed to confirm these findings, this study offers an intriguing glimpse into a new avenue of research in this field.
Date :
  1. Date Completed 1999-05-28
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

10047931

DOI: Digital Object Identifier

10.1097/00002826-199901000-00006

Related Literature

Article Analysis
・Side Effects of rimantadine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.