Disturbance of myocardial energy liberation in experimental charcoal embolism of canine pulmonary artery.

Author: HatanakaY, IshiyamaT, MoritaY, TanimotoT, UenoT

Paper Details 
Original Abstract of the Article :
Experimental charcoal embolism of the pulmonary artery was produced in dogs. Changes in hemodynamics, electrophysiology, and cardiac energy liberation were observed. The effects of histaminic and antihistaminic drugs on these changes were also studied. After two infusions of charcoal suspension, acu...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1031959

データ提供:米国国立医学図書館(NLM)

Myocardial Energy Liberation: A Delicate Balance in the Desert of the Heart

The heart, a tireless desert oasis, is constantly pumping blood throughout the body. This study, like a meticulous researcher analyzing the intricacies of the heart's ecosystem, explores the effects of charcoal embolism on myocardial energy liberation in dogs. The researchers, like skilled surgeons, investigated the changes in hemodynamics, electrophysiology, and mitochondrial function following the experimental procedure.

Uncoupling Oxidative Phosphorylation: A Disruption in the Heart's Energy Supply

The study reveals that charcoal embolism, like a disruptive sandstorm, can significantly alter myocardial energy liberation. The researchers observed uncoupling of oxidative phosphorylation in mitochondria isolated from both ventricles of the dogs. This finding suggests that charcoal embolism can impair the heart's ability to generate energy, potentially leading to cardiac dysfunction.

Understanding the Heart's Resilience: A Path Towards Better Care

This research, like a valuable roadmap in a vast desert, provides crucial insights into the delicate balance of myocardial energy liberation. The study's findings highlight the importance of maintaining adequate oxygen supply and mitochondrial function for optimal cardiac performance.

Dr.Camel's Conclusion

This research, like a careful examination of a desert oasis, delves into the intricate mechanisms of myocardial energy liberation. The findings underscore the vulnerability of the heart to disruptions in its delicate energy balance, emphasizing the need for careful monitoring and intervention when necessary.

Date :
  1. Date Completed 1978-02-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1031959

DOI: Digital Object Identifier

1031959

Related Literature

SNS
PICO Info
in preparation
Languages

English

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