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Is amoxapine an atypical antipsychotic? Positron-emission tomography investigation of its dopamine2 and serotonin2 occupancy.
Author: ChoR, JonesC, KapurS, McKayG, ZipurskyR B
Original Abstract of the Article :
All currently available atypical antipsychotics have, at clinically relevant doses: i) high serotonin (5-HT)2 occupancy; ii) greater 5-HT2 than dopamine (D)2 occupancy; and iii) a higher incidence of extrapyramidal side effects when their D2 occupancy exceeds 80%. A review of pharmacologic and behav...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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引用元:
https://doi.org/10.1016/s0006-3223(98)00204-2
データ提供:米国国立医学図書館(NLM)
Delving into the Neurobiology of Amoxapine: Atypical Antipsychotic or Not?
The world of [psychiatry] is always looking for new ways to understand and treat [mental illness]. This study examines the [neurochemical properties] of [amoxapine], a medication used to treat [depression] and [psychosis], to see if it qualifies as an [atypical antipsychotic]. It's like carefully examining a desert flower, seeking clues to its unique properties.
Unveiling the Neurochemical Profile of Amoxapine
The study utilized [positron-emission tomography (PET)] to investigate how [amoxapine] interacts with [dopamine (D)2] and [serotonin (5-HT)2] receptors in the brain. The results show that [amoxapine] shares some characteristics with [atypical antipsychotics] but also exhibits some differences. It's like discovering a new desert plant that has some familiar traits but also some unique characteristics.
A Deeper Understanding of Antipsychotic Medications: A Journey of Exploration
This study is a valuable step in understanding the [neurobiology] of [amoxapine] and its potential role in the treatment of [mental illness]. It's a reminder that [medical research] is an ongoing journey of exploration, seeking to unlock the mysteries of the human brain and improve patient care. It's like embarking on a journey through a vast and complex desert, seeking knowledge and understanding along the way.
Dr. Camel's Conclusion
This study adds to our knowledge of the [neurochemical mechanisms] involved in [mental illness] and the potential role of [amoxapine] in treating these conditions. It's a reminder that the world of [psychiatry] is a dynamic field, where ongoing research and exploration are key to finding new solutions and improving patient outcomes. The desert of [mental illness] is vast and complex, but with continued research and understanding, we can find new oases of hope and healing.
Date :
- Date Completed 2000-01-05
- Date Revised 2019-08-15
Further Info :
Related Literature
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