Three-day antibiotic therapy with azithromycin and tinidazole plus lansoprazole or pantoprazole to cure Helicobacter pylori infection: a pilot study.

Author: AddoloratoG, ArmuzziA, CammarotaG, CannizzaroO, CianciR, GasbarriniA, GasbarriniG B, PapaA

Paper Details 
Original Abstract of the Article :
The aim of the present study was to investigate and compare the effects of two proton-pump inhibitors, lansoprazole (Limpidex 30 mg, Sigmatau) vs pantoprazole (Peptazol 40 mg, Boehringer Mannheim), included in a three-day antibiotic therapy regimen with azithromycin (Zitromax 500 mg, Pfizer) and tin...See full text at original site
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引用元:
https://doi.org/10.1097/00042737-199903000-00007

データ提供:米国国立医学図書館(NLM)

Three-Day Antibiotic Therapy for Helicobacter pylori Infection: A Pilot Study

The eradication of Helicobacter pylori infection, a common cause of gastritis and peptic ulcers, is a significant goal in gastroenterology. This pilot study aimed to investigate and compare the efficacy of two proton-pump inhibitors, lansoprazole and pantoprazole, as part of a three-day antibiotic therapy regimen for Helicobacter pylori infection. The researchers recruited patients and randomly assigned them to receive either lansoprazole or pantoprazole in combination with azithromycin and tinidazole. The study aimed to assess the effectiveness of each regimen in eradicating Helicobacter pylori infection within a short timeframe.

A Promising Approach for Rapid H. pylori Eradication

The results of this pilot study suggest that both lansoprazole and pantoprazole, when combined with azithromycin and tinidazole, offer a promising approach for rapidly eradicating Helicobacter pylori infection. This short-course therapy regimen could potentially improve patient adherence and reduce treatment costs, making it a valuable tool for managing H. pylori infection.

Optimizing Treatment Strategies for H. pylori Infection

This research emphasizes the importance of optimizing treatment strategies for Helicobacter pylori infection. The study's findings suggest that a three-day antibiotic regimen with proton-pump inhibitors could be an effective approach, particularly in terms of patient convenience and cost-effectiveness. However, further research is needed to confirm these findings and evaluate the long-term efficacy and safety of this treatment approach.

Dr.Camel's Conclusion

Just as a desert oasis can offer respite from the scorching heat, a short-course antibiotic regimen can offer a quick and effective solution for eradicating H. pylori infection. This study highlights the potential of this approach, but further research is needed to ensure its long-term effectiveness and safety, allowing us to better navigate the challenges of managing this common and persistent infection.

Date :
  1. Date Completed 1999-06-25
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

10333196

DOI: Digital Object Identifier

10.1097/00042737-199903000-00007

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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