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Original Abstract of the Article :
Mirtazapine is a presynaptic alpha-2 antagonist that has dual action by increasing noradrenergic and serotonergic neurotransmission. The enhancement of serotonergic neurotransmission is specifically mediated via 5-HT1 receptors because mirtazapine is a postsynaptic serotonergic 5-HT2 and 5-HT3 antag...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1016/s0165-0327(98)00224-9
データ提供:米国国立医学図書館(NLM)
Mirtazapine: A Beacon of Hope in the Desert of Depression
Depression is a pervasive and debilitating condition that casts a dark shadow over the lives of millions. The quest for effective and well-tolerated treatments for depression is ongoing, and mirtazapine, a presynaptic alpha-2 antagonist, has emerged as a promising candidate. This study provides a comprehensive review of the clinical evidence surrounding mirtazapine, exploring its efficacy, safety, and tolerability in treating major depression. The researchers delve into the unique pharmacodynamic properties of mirtazapine, highlighting its dual action on noradrenergic and serotonergic neurotransmission, along with its specific receptor interactions. They also examine the pharmacokinetic profile of mirtazapine, considering its absorption, metabolism, and potential interactions with other medications. The authors present compelling evidence that mirtazapine is an effective, safe, and well-tolerated antidepressant, offering a valuable alternative to existing treatments.
Mirtazapine: A Reliable Compass in the Depressive Labyrinth
This comprehensive review provides compelling evidence that mirtazapine is a valuable tool for treating major depression. The study's findings, based on extensive clinical trials, demonstrate mirtazapine's effectiveness, safety, and tolerability, offering a valuable alternative to existing treatments.
Navigating the Desert of Despair: Finding Hope in Mirtazapine
The desert of depression can be a lonely and desolate place, but mirtazapine offers a beacon of hope. As Dr. Camel, I’ve learned that navigating this arid landscape requires a strong and reliable compass, and mirtazapine seems to provide that guidance for many individuals struggling with depression.
Dr.Camel's Conclusion
Mirtazapine, with its unique pharmacodynamic properties, stands as a valuable addition to the antidepressant armamentarium. This research provides compelling evidence for its effectiveness, safety, and tolerability in treating major depression, offering a beacon of hope for those navigating the challenging desert of this prevalent condition.
Date :
- Date Completed 1999-06-28
- Date Revised 2019-09-05
Further Info :
Related Literature
English
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