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Preincisional dextromethorphan treatment decreases postoperative pain and opioid requirement after laparoscopic cholecystectomy.

Author: HoS T, LiC Y, LiuS T, WongC S, WuC T, YehC C, YuJ C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Preincisional treatment with dextromethorphan (DM) was found to provide preemptive analgesia in patients undergoing laparoscopic cholecystectomy. DM administered before surgery resulted in a longer time to first meperidine injection, lower total meperidine consumption, and lower worst pain scores compared to DM administered after surgery.
Paper Details　
Original Abstract of the Article :
In the present study, we examined whether preincisional treatment with dextromethorphan (DM) provides preemptive analgesia. Ninety patients scheduled for laparoscopic cholecystectomy were included. Patients receiving chlorpheniramine maleate (CPM) 20 mg via an IM injection 30 min before skin incisio...See full text at original site
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引用元：
https://doi.org/10.1097/00000539-199906000-00025

データ提供：米国国立医学図書館（NLM）

Preincisional Dextromethorphan for Postoperative Pain: A Desert Oasis of Preemptive Analgesia

The [management of postoperative pain] is a crucial aspect of patient care. This study explores the [effectiveness of preincisional dextromethorphan (DM) for preemptive analgesia] following [laparoscopic cholecystectomy]. The authors demonstrate that [preincisional DM] significantly reduces [postoperative pain and opioid requirements] compared to [postoperative DM] or [control group]. This study suggests that [preincisional DM] can effectively prevent postoperative pain, offering a promising strategy for improving patient comfort and reducing opioid use. This research has important implications for [postoperative pain management], potentially leading to improved patient outcomes and reduced reliance on opioids.

Dextromethorphan: A Desert Oasis of Pain Relief

This research is like discovering a hidden oasis in the vast desert of postoperative pain management. The authors show that [preincisional DM] is highly effective in reducing pain and opioid requirements, offering a promising strategy for improving patient comfort and well-being. This discovery highlights the importance of [preemptive analgesia], demonstrating that by addressing pain early, we can significantly improve patients' recovery experience.

Navigating the Desert of Postoperative Pain: What to Remember

Postoperative pain is a common experience, but with effective pain management strategies, it can be minimized. This research suggests that [preincisional DM] is a valuable tool in the fight against postoperative pain, offering a potential pathway for reducing opioid reliance and improving patient recovery. Remember, managing pain effectively is essential for a smoother recovery experience.

Dr.Camel's Conclusion

This study is like a refreshing oasis in the vast and sometimes challenging desert of postoperative pain management. The discovery of [preincisional DM] as an effective pain relief strategy offers hope for a more comfortable and less opioid-dependent recovery experience for patients.

Date :
  1. Date Completed 1999-06-15
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

10357340

DOI: Digital Object Identifier

10.1097/00000539-199906000-00025

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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