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A comparison of the effect of three sedatives on esophageal sphincters in cats.

Author: CroffieJ M, EllettM L, FitzgeraldJ F, LouQ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Young children often need sedation for esophageal motility studies. This study in cats looked for a safe and effective oral sedative to replace an intramuscular cocktail, which can be traumatic.
Paper Details　
Original Abstract of the Article :
Children 5 years old and younger often require sedation for esophageal motility studies (EMS). At our institution, an intramuscular cocktail of meperidine, promethazine and chlorpromazine (MPC) has been used as the standard sedative for young children undergoing EMS. Administering the intramuscular ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1159/000016913

データ提供：米国国立医学図書館（NLM）

A Comparative Study of Sedatives for Esophageal Motility Studies

This research explores the use of sedatives in young children undergoing esophageal motility studies (EMS). It's like navigating the challenging terrain of a desert, where each step requires careful consideration and the right tools for success. The researchers investigated the effects of three different sedatives, meperidine, promethazine, and chlorpromazine (MPC), on esophageal sphincter function in cats, a model system for studying human physiology.

Seeking Safer Sedation: A Quest for Optimal Esophageal Motility Studies

The study's objective is to find a safe and effective orally-administered sedative for young children undergoing EMS. It's like searching for a hidden oasis in the vast desert of medical research, aiming to improve the experience for both children and their families. The researchers compared the effects of the intramuscular cocktail MPC with two orally-administered sedatives, seeking to identify the best option for pediatric patients.

Implications for Pediatric Health and Future Research

This research provides valuable information for pediatric healthcare providers, informing the choice of sedation for young children undergoing esophageal motility studies. It's like uncovering a hidden treasure in the desert, leading to better care and improved outcomes for children. The findings highlight the need for further research into the effects of various sedatives on esophageal motility in children, ensuring the safest and most effective treatment options for these young patients.

Dr.Camel's Conclusion

This research exemplifies the ongoing quest for safer and more effective medical procedures for children. It's like navigating a vast and challenging desert, but the goal is clear: to provide the best possible care for our youngest patients. The study's findings offer hope for a future where pediatric healthcare is more compassionate, efficient, and effective.

Date :
  1. Date Completed 1999-12-09
  2. Date Revised 2017-11-01
Further Info :

Pubmed ID

10545717

DOI: Digital Object Identifier

10.1159/000016913

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Article Analysis
・Side Effects of promethazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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