Effect of beta-cyclodextrin complexation on the photochemical and photosensitizing properties of tolmetin: a steady-state and time-resolved study.

Author: De GuidiG, MontiS, ScaianoJ C, SortinoS

Paper Details 
Original Abstract of the Article :
The effects of beta-cyclodextrin complexation on the photochemical and photosensitizing properties of tolmetin have been investigated. Absorption, emission, circular dichroism and NMR measurements were used to characterize the host-guest complex. Nanosecond laser flash photolysis and steady-state ph...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/10546551

データ提供:米国国立医学図書館(NLM)

Shining a Light on Tolmetin: Cyclodextrin's Protective Power

Tolmetin is a medication commonly used to treat pain and inflammation. But like many medications, it can have side effects. This study explores the use of beta-cyclodextrin, a type of sugar molecule, to protect against the damaging effects of tolmetin when exposed to light.

Protecting Against Light: A Shield in the Desert

The researchers found that beta-cyclodextrin forms a protective shield around tolmetin, preventing it from breaking down when exposed to light. This could be important for keeping the drug stable and effective, especially if it needs to be exposed to light during storage or administration.

Safely Navigating the Desert of Medication: A Lesson from Cyclodextrin

This study highlights the potential benefits of using beta-cyclodextrin to protect medications from the damaging effects of light. It also shows how important it is to store medications properly to maintain their effectiveness and safety. Keep those medications out of direct sunlight!

Dr.Camel's Conclusion

This study reveals the interesting protective effect of beta-cyclodextrin on tolmetin when exposed to light. It provides valuable insight into enhancing drug stability and minimizing unwanted side effects. By understanding the interaction between these molecules, we can improve medication effectiveness and safety, making the desert of pharmaceutical research a bit more navigable.

Date :
  1. Date Completed 1999-12-06
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

10546551

DOI: Digital Object Identifier

10546551

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English

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