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Additional methadone increases craving for heroin: a double-blind, placebo-controlled study of chronic opiate users receiving methadone substitution treatment.
Author: BoltonJ, CurranH V, SmythC, WanigaratneS
Original Abstract of the Article :
AIMS: To assess the acute-on-chronic effects of methadone on drug craving, mood and cognitive and psychomotor functioning in patients on long-term methadone substitution treatment. DESIGN AND PARTICIPANTS: A double-blind, cross-over design was used to compare the effects of a 33% increase in patien...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1046/j.1360-0443.1999.9456654.x
データ提供:米国国立医学図書館(NLM)
Methadone and Heroin Craving: Navigating the Desert of Addiction
The desert of addiction is a treacherous landscape, where cravings for drugs can be a relentless force, like a sandstorm that threatens to engulf the traveler. Researchers are constantly searching for ways to help those struggling with addiction, exploring the complexities of medication-assisted treatment, like seeking a safe passage through this unforgiving terrain. This study examines the effects of methadone, a medication used to treat opioid addiction, on heroin cravings in individuals receiving methadone substitution therapy.
The authors meticulously analyze the data from a double-blind, placebo-controlled study, seeking to understand the impact of methadone on cravings, mood, and cognitive function. Their findings reveal a surprising and concerning outcome: additional methadone significantly increased both positive and negative cravings for heroin. This unexpected discovery, like stumbling upon a hidden danger in the desert, highlights the complexities of addiction and the need for careful consideration of treatment strategies.
A Shifting Landscape: The Complexities of Addiction Treatment
The authors' findings challenge the conventional view of methadone as a simple solution for heroin addiction. They suggest that methadone, while effective in reducing withdrawal symptoms, may also inadvertently increase cravings, potentially hindering the journey to recovery. This is like discovering a hidden oasis that turns out to be a mirage, a deceptive illusion that masks the true dangers of the desert.
Dr. Camel's Conclusion
The desert of addiction is a place of constant change, where the landscape shifts and the dangers are often hidden from view. This study reminds us that addiction is a complex and multifaceted disease, requiring careful navigation and tailored treatment strategies. The authors' findings, like a warning sign in the desert, highlight the importance of understanding the potential risks and benefits of medication-assisted treatment. We must be ever vigilant in our search for solutions to this challenging problem.
Date :
- Date Completed 1999-11-24
- Date Revised 2019-09-15
Further Info :
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